Recombinant Mouse Fibroblast Growth Factor 21, His-tagged
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Cat.No. : | Fgf21-110M Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Mouse Fibroblast Growth Factor-21 produced inE.Coliis a single, non-glycosylated, polypeptide chain containing 183 amino acids including N-terminal Methionin and having a molecular mass of 20.1 kDa. The amino acid sequence of the recombinant mouse FGF21 is 100% homologous to the amino acid sequence of the Mouse FGF21 without signal sequence and contains 14a.a. His-tagged at N-terminal. The FGF-21 is purified by proprietary chromatographic techniques. |
Description : | FGF-21 is preferentially expressed in liver, but an exact knowledge of FGF-21 bioactivity and its mode of action have been lacking to date. FGF-21 is a potent activator of glucose uptake on adipocytes, protects animals from diet-induced obesity when overexpressed in transgenic mice, and lowers blood glucose and triglyceride levels when therapeutically administered to diabetic rodents. |
Source : | Escherichia Coli. |
Amino Acid Sequence : | MRGSHHHHHHGMASAY PIPDSSPLLQ FGGQVRQRYL YTDDDQDTEA HLEIREDGTV VGAAHRSPES LLELKALKPG VIQILGVKAS RFLCQQPDGA LYGSPHFDPE ACSFRELLLE DGYNVYQSEA HGLPLRLPQK DSPNQDATSW GPVRFLPMPG LLHEPQDQAG FLPPEPPDVG SSDPLSMVEP LQGRSPSYAS |
Physical Appearance : | Sterile Filtered white lyophilized powder. |
Purity : | Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
Formulation : | Filtered (0.4 µm) and lyophilized from 0.5 mg/ml in 20 mM TRIS, 20 mM NaCl, pH 7.5. |
Solubility : | It is recommended to reconstitute the lyophilized Fibroblast Growth Factor-21 Mouse Recombinant in sterile 18 MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
Stability : | Recombinant Mouse Lyophilized FGF-21 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Fibroblast Growth Factor 21 should be stored at 4°Cbetween 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Gene Name : | Fgf21 fibroblast growth factor 21 [ Mus musculus ] |
Synonyms : | Fgf21; fibroblast growth factor 21 |
Gene ID : | 56636 |
mRNA Refseq : | NM_020013 |
Protein Refseq : | NP_064397 |
UniProt ID : | Q9JJN1 |
Chromosome Location : | 7 B2 |
Pathway : | MAPK signaling pathway; Melanoma; Pathways in cancer; Regulation of actin cytoskeleton |
Function : | growth factor activity |
◆ Recombinant Protein
FGF21-287F | Recombinant Human FGF21 Protein, His-tagged | +Inquiry |
FGF21-930H | Recombinant Human FGF21 Protein, His-tagged | +Inquiry |
FGF21-932P | Recombinant Pig FGF21 Protein, His&GST-tagged | +Inquiry |
FGF21-415F | Recombinant Human FGF21 Protein (182 aa) | +Inquiry |
Fgf21-2997M | Recombinant Mouse Fgf21 Protein, Myc/DDK-tagged | +Inquiry |
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◆ Lysates
FGF21-1890MCL | Recombinant Mouse FGF21 cell lysate | +Inquiry |
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FGF1FGF10FGF12FGF16FGF17FGF18FGF19FGF2FGF20Fgf21Fgf22FGF23FGF4FGF5FGF6FGF7FGF8FGF9Fgf15FGF11FGF3FGF13FGF14
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