Recombinant Full Length Human FGF21 Protein, C-Flag-tagged

• Cat.No.: FGF21-947HFL
• Product Overview: Recombinant Full Length Human FGF21 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 19.4 kDa
• AA Sequence: MDSDETGFEHSGLWVSVLAGLLLGA CQAHPIPDSSPLLQFGGQVRQRYLY TDDAQQTEAHLEIREDGTVG GAADQSPESLLQLKALKPGVIQILG VKTSRFLCQRPDGALYGSLHFDPEA CSFRELLLEDGYNVYQSEAH GLPLHLPGNKSPHRDPAPRGPARFL PLPGLPPAPPEPPGILAPQPPDVGS SDPLSMVGPSQGRSPSYAS
  TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Adult stem cells, Embryonic stem cells, ES Cell Differentiation/IPS, Secreted Protein
• Protein Pathways: MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

Gene Information

• Gene Name: FGF21 fibroblast growth factor 21 [ Homo sapiens (human) ]
• Official Symbol: FGF21
• Synonyms: fibroblast growth factor 21
• Gene ID: 26291
• mRNA Refseq: NM_019113.4
• Protein Refseq: NP_061986.1
• MIM: 609436
• UniProt ID: Q9NSA1