Recombinant Mouse Fgf21, His-tagged
Cat.No. : | Fgf21-503M |
Product Overview : | Total 192 AA. Mw: 21.2 kDa (calculated). N-terminal His-tag, 10 extra AA (highlighted). |
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Cat. No. : | Fgf21-503M |
Description : | Fibroblast growth factor 21 is a protein that in humans is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. |
Source : | E. coli |
Species : | Mouse |
Form : | Filtered (0,4 μm) and lyophilized in 0.5 mg/mL in 20mM TRIS, 20mM NaCl, pH 7.5. |
Purity : | Purity>95% |
Reconstitution : | Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. Add DTT (0.2 mM ) and NaCl (0.1-0.15 M) before freezing to prevent potential aggregation. |
Applications : | ELISA; Western blotting |
Quality Control Test : | BCA to determine quantity of the protein; SDS PAGE to determine purity of the protein; LAL to determine quantity of endotoxin |
Sequences of amino acids : | MKHHHHHHAS AYPIPDSSPL LQFGGQVRQR YLYTDDDQDT EAHLEIREDG TVVGAAHRSP ESLLELKALK PGVIQILGVK ASRFLCQQPD GALYGSPHFD PEACSFRELL LEDGYNVYQS EAHGLPLRLP QKDSPNQDAT SWGPVRFLPM PGLLHEPQDQ AGFLPPEPPD VGSSDPLSMV EPLQGRSPSY AS |
Storage : | Store lyophilized protein at -20°C. Lyophilized protein remains stable until the expiry date when stored at -20°C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at -80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after one week at 4°C. |
Gene Name : | Fgf21 fibroblast growth factor 21 [ Mus musculus ] |
Official Symbol : | Fgf21 |
Synonyms : | Fgf21; fibroblast growth factor 21 |
Gene ID : | 56636 |
mRNA Refseq : | NM_020013 |
Protein Refseq : | NP_064397 |
UniProt ID : | Q9JJN1 |
Chromosome Location : | 7B2 |
Pathway : | ESC Pluripotency Pathways; MAPK signaling pathway; Melanoma; Pathways in cancer; Regulation of Actin Cytoskeleton; Regulation of actin cytoskeleton |
Function : | growth factor activity |
Products Types
◆ Recombinant Protein | ||
Fgf21-931R | Recombinant Rat Fgf21 Protein, His-tagged | +Inquiry |
Fgf21-257M | Active Recombinant Mouse Fgf21 Protein (Ala29-Ser210), N-His tagged, Animal-free, Carrier-free | +Inquiry |
Fgf21-1491R | Recombinant Rat Fgf21 Protein, His-tagged | +Inquiry |
FGF21-034H | Active Recombinant Human FGF21 Protein | +Inquiry |
Fgf21-2997M | Recombinant Mouse Fgf21 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
FGF21-1890MCL | Recombinant Mouse FGF21 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionFGF21 expression in adipose tissue is regulated by various factors, including peroxisome proliferator-activated receptor gamma (PPARγ) activation.
FGF21 influences lipid metabolism by promoting the utilization of fatty acids for energy, contributing to the regulation of lipid homeostasis.
FGF21 levels are being explored as potential biomarkers for metabolic health, reflecting conditions such as insulin resistance and metabolic syndrome.
Yes, FGF21 plays a role in improving insulin sensitivity, making it a potential target for interventions in insulin resistance-associated conditions.
Yes, FGF21 influences energy expenditure by promoting thermogenesis in brown adipose tissue, contributing to overall metabolic regulation.
Gender-specific differences in FGF21 levels have been reported, with some studies suggesting higher circulating FGF21 concentrations in females.
FGF21 activates signaling pathways such as the AMP-activated protein kinase (AMPK) pathway, which contributes to its metabolic effects.
Customer Reviews (3)
Write a reviewThe manufacturer's history of producing high-quality products contributed to our trust in this protein.
Collaboration with other research groups was made easier by the product's standardized use in the scientific community.
The product's role in promoting collaboration and teamwork positively impacted the quality of our research.
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