| Description : |
Predicted to enable peptidyl-dipeptidase inhibitor activity. Involved in mesenchymal cell proliferation involved in ureteric bud development. Acts upstream of or within several processes, including animal organ development; positive regulation of transport; and regulation of signal transduction. Located in lysosome and plasma membrane. Is anchored component of plasma membrane. Is expressed in several structures, including branchial arch; future brain; lower jaw; reproductive system; and urinary system. Used to study Simpson-Golabi-Behmel syndrome type 1. Human ortholog(s) of this gene implicated in Simpson-Golabi-Behmel syndrome type 1; hepatocellular carcinoma; and nephroblastoma. Orthologous to human GPC3 (glypican 3). |
| Source : |
HEK293 |
| Species : |
Mouse |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
62.4 kDa |
| Protein Length : |
579 |
| AA Sequence : |
MAGTVRTACLLVAMLLGLGCLGQAQ PPPPPDATCHQVRSFFQRLQPGLKW VPETPVPGSDLQVCLPKGPTCCSRK MEEKYQLTARLNMEQLLQSASMELK FLIIQNAAVFQEAFEIVVRHAKNYT NAMFKNNYPSLTPQAFEFVGEFFTD VSLYILGSDINVDDMVNELFDSLFP VIYTQMMNPGLPESVLDINECLRGA RRDLKVFGSFPKLIMTQVSKSLQVT RIFLQALNLGIEVINTTDHLKFSKD CGRMLTRMWYCSYCQGLMMVKPCGG YCNVVMQGCMAGVVEIDKYWREYIL SLEELVNGMYRIYDMENVLLGLFST IHDSIQYVQKNGGKLTTTIGKLCAH SQQRQYRSAYYPEDLFIDKKILKVA HVEHEETLSSRRRELIQKLKSFINF YSALPGYICSHSPVAENDTLCWNGQ ELVERYSQKAARNGMKNQFNLHELK MKGPEPVVSQIIDKLKHINQLLRTM SVPKGKVLDKSLDEEGLESGDCGDD EDECIGSSGDGMVKVKNQLRFLAEL AYDLDVDDAPGNKQHGNQKDNEITT SHSVGNMPSPLKILISVAIYVACFF FLVH |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
