- Cynomolgus monkey(2)
- Rhesus Macaque(1)
Recombinant Human GPC3 Protein (S359F), His-tagged, low endotoxin, FITC conjugated
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||June 03, 2023||Add to Quote|
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|Cat.No. :||GPC3-2246HF Optional Service: Optional requirements on this protein|
|Product Overview :||FITC conjugated recombinant human GPC3 (S359F, Gln25-His559)(low endotoxin) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).|
|Description :||Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3/GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.|
|Molecular Mass :||The protein has a calculated MW of 61.7 kDa. The protein migrates as 66-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.|
|Protein length :||Gln25-His559|
|N-terminal Sequence Analysis :||Gln 25|
|Endotoxin :||< 0.1 EU/ μg by the LAL method.|
|Purity :||> 90 % as determined by SDS-PAGE|
|Characteristic :||Disulfide-linked homodimer
Labeled with FITC via amines
Excitation source: 488 nm spectral line, argon-ion laser
Excitation Wavelength: 488 nm
Emission Wavelength: 535 nm
|Storage :||For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
|Storage Buffer :||Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.|
|Reconstitution :||It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.|
|Gene Name :||GPC3|
|Official Symbol :||GPC3|
|Synonyms :||GPC3; glypican 3; SDYS; glypican-3; DGSX; glypican proteoglycan 3; OCI 5; SGB; SGBS; SGBS1; secreted glypican-3; intestinal protein OCI-5; heparan sulphate proteoglycan; MXR7; OCI-5; GTR2-2|
|Gene ID :||2719|
|mRNA Refseq :||NM_001164617|
|Protein Refseq :||NP_001158089|
|UniProt ID :||P51654|
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