Active Recombinant Mouse Ifng Protein

• Cat.No.: Ifng-078M
• Product Overview: Purified recombinant protein of Mouse interferon gamma (Ifng) without tag was expressed in E.coli.

Specification

• Description: This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mice deficient in this gene have increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.
• Source: E. coli
• Species: Mouse
• Bio-activity: Determined by its ability to inhibit the proliferation of murine WEHI-279 cells. The expected ED50 is less than or equal to 0.2 ng/ml, corresponding to a specific activity of > 5 x 10^6 units/mg.
• Molecular Mass: 15.6 kDa
• AA Sequence: MHGTVIESLESLNNYFNSSGIDVEE KSLFLDIWRNWQKDGDMKILQSQII SFYLRLFEVLKDNQAISNNISVIES HLITTFFSNSKAKKDAFMSIAKFEV NNPQVQRQAFNELIRVVHQLLPESS LRKRKRSRC
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Purity: >95%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.
• Storage: Store at -80 centigrade.
• Storage Buffer: Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2
• Reconstitution: Resuspend the protein in the desired concentration in proper buffer.

Gene Information

• Gene Name: Ifng interferon gamma [ Mus musculus (house mouse) ]
• Official Symbol: Ifng
• Synonyms: Ifng; interferon gamma; Ifg; IFN-g; interferon gamma; IFN-gamma; gamma interferon
• Gene ID: 15978
• mRNA Refseq: NM_008337
• Protein Refseq: NP_032363
• UniProt ID: P01580