Recombinant Mouse Igf1 Protein


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Recombinant Mouse Igf1 Protein

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Cat.No. : Igf1-079M
Product Overview : Purified recombinant protein of Mouse insulin-like growth factor 1 (Igf1), transcript variant 1 (Gly49-Ala118) without tag was expressed in E.coli.
Description : This gene encodes a member of the insulin-like growth factor (IGF) family of proteins that promote growth and development during fetal and postnatal life. This gene is predominantly expressed in the liver and the encoded protein undergoes proteolytic processing to generate a disulfide-linked mature polypeptide. Transgenic disruption of this gene in mice results in reduced postnatal survival and severe growth retardation. Mice lacking the encoded protein exhibit generalized organ hypoplasia including underdevelopment of the central nervous system and developmental defects in bone, muscle and reproductive systems. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.
Source : E. coli
Species : Mouse
Bio-activity : The ED50 is 3-15 ng/ml, corresponding to a specific activity of 0.6-3.3 x 105 units/mg, determined by the dose dependent stimulation of MCF-7 cell proliferation.
Molecular Mass : 7.8 kDa
Endotoxin : Less than 0.01 ng per µg protein as determined by the LAL method
Purity : >95%, as determined by SDS-PAGE and Coomassie blue staining
Stability : Unopened vial can be stored between 2 centigrade and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 centigrade and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Storage : Store at -80 centigrade.
Concentration : Protein formulated and vialed at >50 ug/mL in specified buffer
Storage Buffer : 1 x PBS
Figure :

Gene Name : Igf1 insulin-like growth factor 1 [ Mus musculus (house mouse) ]
Official Symbol : Igf1
Synonyms : Igf1; insulin-like growth factor 1; Igf-1; Igf-I; C730016P09Rik; insulin-like growth factor I; somatomedin
Gene ID : 16000
mRNA Refseq : NM_010512
Protein Refseq : NP_034642
UniProt ID : P05017
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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