Recombinant Mouse IL10RA protein, His/GST-tagged

• Cat.No.: IL10RA-56M
• Product Overview: Recombinant Mouse IL10RA protein, fused to His/GST-tag, was expressed in E. coli.

Specification

• Description: Predicted to enable interleukin-10 binding activity and interleukin-10 receptor activity. Predicted to be involved in several processes, including negative regulation of autophagy; positive regulation of receptor signaling pathway via JAK-STAT; and ubiquitin-dependent endocytosis. Predicted to be located in cytosol. Predicted to be integral component of plasma membrane. Predicted to colocalize with plasma membrane. Human ortholog(s) of this gene implicated in inflammatory bowel disease 28. Orthologous to human IL10RA (interleukin 10 receptor subunit alpha).
• Source: E. coli
• Species: Mouse
• Tag: His/GST
• Form: Supplied as a 0.2 μm filtered solution in 100mM NaHCO3, 500mM NaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl.
• Molecular Mass: ~53.3 kDa
• AA Sequence: MSPILGYWKIKGLVQPTRLLLEYLE EKYEEHLYERDEGDKWRNKKFELGL EFPNLPYYIDGDVKLTQSMAIIRYI ADKHNMLGGCPKERAEISMLEGAVL DIRYGVSRIAYSKDFETLKVDFLSK LPEMLKMFEDRLCHKTYLNGDHVTH PDFMLYDALDVVLYMDPMCLDAFPK LVCFKKRIEAIPQIDKYLKSSKYIA WPLQGWQATFGGGDHPPKSDLVPRG SHHHHHHLEFIAYGTELPSPSYVWF EARFFQHILHWKPIPNQSESTYYEV ALKQYGNSTWNDIHICRKAQALSCD LTTFTLDLYHRSYGYRARVRAVDNS QYSNWTTTETRFTVDEVILTVDSVT LKAMDGIIYGTIHPPRPTITPAGDE YEQVFKDLRVYKISIRKFSELKNAT KRVKQETFTLTVPIGVRKFCVKVLP RLESRINKAEWSEEQCLLITTEQYF TVTNLSI
• Purity: >90%
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.21 mg/mL

Gene Information

• Gene Name: Il10ra interleukin 10 receptor, alpha [ Mus musculus (house mouse) ]
• Official Symbol: IL10RA
• Synonyms: Il10r; CDw210; CDw210a; IL-10R1; IL-10RA; mIL-10R; AW553859
• Gene ID: 16154
• mRNA Refseq: NM_008348
• Protein Refseq: NP_032374
• UniProt ID: Q61727