| Description : |
Predicted to enable cytokine binding activity and interleukin-23 receptor activity. Predicted to contribute to interleukin-12 receptor binding activity and interleukin-23 binding activity. Predicted to be involved in several processes, including positive regulation of defense response to virus by host; regulation of cytokine production; and response to interferon-gamma. Predicted to act upstream of or within leukocyte mediated immunity and receptor signaling pathway via JAK-STAT. Predicted to be integral component of plasma membrane. Predicted to be part of interleukin-23 receptor complex. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); inflammatory bowel disease (multiple); pulmonary hypertension; rhinitis; and systemic scleroderma. Orthologous to human IL23R (interleukin 23 receptor). |
| Source : |
HEK293 |
| Species : |
Mouse |
| Tag : |
Fc |
| Form : |
Lyophilized |
| Molecular Mass : |
66.8 kDa |
| Protein Length : |
644 |
| AA Sequence : |
MSHLTLQLHVVIALYVLFRWCHGGI TSINCSGDMWVEPGEIFQMGMNVSI YCQEALKHCRPRNLYFYKNGFKEEF DITRINRTTARIWYKGFSEPHAYMH CTAECPGHFQETLICGKDISSGHPP DAPSNLTCVIYEYSGNMTCTWNTGK PTYIDTKYIVHVKSLETEEEQQYLA SSYVKISTDSLQGSRKYLVWVQAVN SLGMENSQQLHVHLDDIVIPSASII SRAETTNDTVPKTIVYWKSKTMIEK VFCEMRYKTTTNQTWSVKEFDANFT YVQQSEFYLEPDSKYVFQVRCQETG KRNWQPWSSPFVHQTSQETGKRNWQ PWSSPFVHQTSQTVSQVTAKSSHEP QKMEMLSATIFRGHPASGNHQDIGL LSGMVFLAIMLPIFSLIGIFNRSLR IGIKRKVLLMIPKWLYEDIPNMENS NVAKLLQEKSVFENDNASEQALYVD PVLTEISEISPLEHKPTDYKEERLT GLLETRDCPLGMLSTSSSVVYIPDL NTGYKPQVSNVPPGGNLFINRDERD PTSLETTDDHFARLKTYPNFQFSAS SMALLNKTLILDELCLVLNQGEFNS LDIKNSRQEETSIVLQSDSPSETIP AQTLLSDEFVSCLAIGNEDLPSINS YFPQNVLESHFSRISLFQK |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
