IL23R involved in several pathways and played different roles in them. We selected most pathways IL23R participated on our site, such as Cytokine-cytokine receptor interaction, IL23-mediated signaling events, Inflammatory bowel disease (IBD), which may be useful for your reference. Also, other proteins which involved in the same pathway with IL23R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Cytokine-cytokine receptor interaction |
IL18RAP; EDAR; IL1A; MPL; TNFRSF11B; IFNAR2; TNFRSF10C; Ccl12; IFNW1; IL2RG |
| IL23-mediated signaling events |
IL24; IL17F; IL23R |
| Inflammatory bowel disease (IBD) |
TGFB2; TNF; TLR2; STAT3; TGFB3; H2-AB1; IFNG; HLA-DOA; STAT4; TGFB1 |
| Jak-STAT signaling pathway |
STAT1B; IL13RA2; IFNA5; Gh; LEPR; PRL; CSH; CCND2A; PIAS4A; IL5 |
IL23R has several biochemical functions, for example, contributes_to interleukin-12 receptor binding, contributes_to interleukin-23 binding, contributes_to interleukin-23 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL23R itself. We selected most functions IL23R had, and list some proteins which have the same functions with IL23R. You can find most of the proteins on our site.
| Function |
Related Protein |
| contributes_to interleukin-12 receptor binding |
IL12B; IL12RB1; IL23R |
| contributes_to interleukin-23 binding |
IL12RB1; IL23R |
| contributes_to interleukin-23 receptor activity |
IL23R; IL12RB1 |
| protein binding |
DDB1; FAM122A; SOCS5; NAMPT; FIGNL1; C1GALT1C1; PDCD5; DSN1; HNRNPH1; PUM1 |
IL23R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL23R here. Most of them are supplied by our site. Hope this information will be useful for your research of IL23R.
C1D
Ciccacci, C; Perricone, C; et al. A Multilocus Genetic Study in a Cohort of Italian SLE Patients Confirms the Association with STAT4 Gene and Describes a New Association with HCP5 Gene. PLOS ONE 9:-(2014).
Tillack, C; Ehmann, LM; et al. Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-gamma-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment. GUT 63:567-577(2014).
