Recombinant Mouse Il31 Protein, His-Tagged
Cat.No. : | Il31-01M |
Product Overview : | Recombinant mouse Il31 Protein, His-tagged was expressed in E. coli cell |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-31 (IL-31) s an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. It is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor β (OSMRβ) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways. |
Source : | Escherichia coli |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized powder |
AA Sequence : | MTCSLSFGAPISKEDLRTTIDLLKQ ESQDLYNNYSIKQASGMSADESIQL PCFSLDREALTNISVIIAHLEKVKV LSENTVDTSWVIRWLTNISCF NPLNLNISVPGNTDESYDCKVFVLT VLKQFSNCMAELQAKDNTTC with polyhistidine tag at the Cterminus |
Endotoxin : | <0.1 EU per 1 μg of the protein by the LAL method. |
Purity : | >98% as determined by SDS-PAGE. Ni-NTA chromatography |
Storage Buffer : | The protein was lyophilized from a solution containing 1X PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Storage : | Lyophilized protein should be stored at -20°C. Upon reconstitution, protein aliquots should be stored at -20°C or -80°C. |
Notes : | Please use within one month after protein reconstitution. |
Gene Name : | Il31 interleukin 31 [ Mus musculus (house mouse) ] |
Official Symbol : | Il31 |
Synonyms : | 1700013B14Rik |
Gene ID : | 76399 |
mRNA Refseq : | NM_029594.2 |
Protein Refseq : | NP_083870.1 |
UniProt ID : | Q6EAL8 |
Products Types
◆ Recombinant Protein | ||
IL31-1038D | Recombinant Dog IL31 Protein, His-tagged | +Inquiry |
IL31-2311H | Recombinant Human IL31 Protein, His-tagged | +Inquiry |
IL31-096I | Active Recombinant Human IL31 Protein (141 aa) | +Inquiry |
Il31-1923M | Recombinant Mouse Il31 Protein | +Inquiry |
IL31-4514M | Recombinant Mouse IL31 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IL31-5227HCL | Recombinant Human IL31 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionThe IL31 may have specificity for specific diseases, with relatively few side effects being a big advantage.
IL31 activates downstream signaling pathways by binding to receptors and participates in inflammatory response and immune regulation.
It has a wide range of applications in immune inflammation, dermatology and other research fields.
Clinical studies of IL31 are ongoing, but there is no clear therapeutic effect and effectiveness assessment at this time.
IL31 research still faces many challenges, including side effect evaluation, efficacy verification and other issues, and further efforts are needed.
Optimal dose may be related to individual differences, disease type and other factors, and the appropriate dose should be determined under the guidance of a doctor when using IL31.
Customer Reviews (3)
Write a reviewIL31 product has strict quality control and complies with relevant industry standards.
It performs well in biological activity tests.
This protein has high yield and good economic benefits.
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