Recombinant Rat Il31 protein, His & GST-tagged

• Cat.No.: Il31-1574R
• Product Overview: Recombinant Rat Il31 aa. (Cys134~Glu262 (Accession # D3ZIP0)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Source: E. coli
• Species: Rat
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 47.9kDa.
• Protein length: Cys134~Glu262 (Accession # D3ZIP0)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method).
• Purity: >95%
• Characteristic: The isoelectric point is 6.4.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Il31 interleukin 31 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Il31
• Synonyms: interleukin-31
• Gene ID: 690028
• mRNA Refseq: XM_017598514.1
• Protein Refseq: XP_017454003.1
• UniProt ID: D3ZIP0

Reviews

04/22/2022

IL31 product has strict quality control and complies with relevant industry standards.

09/26/2021

It performs well in biological activity tests.

09/13/2020

This protein has high yield and good economic benefits.

Q&As

What are the advantages of IL31 compared with other therapeutic methods?

The IL31 may have specificity for specific diseases, with relatively few side effects being a big advantage.

What is the action mechanism of IL31?

IL31 activates downstream signaling pathways by binding to receptors and participates in inflammatory response and immune regulation.

In what research areas is this protein used in the laboratory?

It has a wide range of applications in immune inflammation, dermatology and other research fields.

How is the clinical research progress of IL31?

Clinical studies of IL31 are ongoing, but there is no clear therapeutic effect and effectiveness assessment at this time.

Are there some challenges in the study of IL31?

IL31 research still faces many challenges, including side effect evaluation, efficacy verification and other issues, and further efforts are needed.

How to determine the optimal dose of IL31 for treatment?

Optimal dose may be related to individual differences, disease type and other factors, and the appropriate dose should be determined under the guidance of a doctor when using IL31.