il31

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il31

Official Full Name interleukin 31
Background IL-31 is a cytokine with a four-helix bundle structure, which is preferentially produced by type 2 helper T cells (Th2). The structure of IL-31 places it in the IL-6 family of cytokines. IL-31 signals via a receptor complex that is composed of IL-31 receptor A (IL31RA) and oncostatin M receptor subunits. These receptor subunits are expressed in activated monocytes and in unstimulated epithelial cells.
Synonyms IL31; interleukin 31; interleukin-31; IL 31; IL-31
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Tag :
    • His
    • GST
    • N/A
    • Strep II
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL31-137H Recombinant Human Interleukin 31 E.coli N/A
    Human IL31-284H Recombinant Human IL31, StrepII-tagged Human Cell Strep II
    Human IL31-311H Recombinant Human IL31, His-tagged Human Cell His
    Human IL31-4336HG GMP Recombinant Human IL31 protein E.coli N/A
    Human IL31-5227HCL Recombinant Human IL31 293 Cell Lysate HEK293 N/A
    Human IL31-641H Recombinant Human IL31 protein E.coli N/A
    Mouse Il31-1573M Recombinant Mouse Il31 protein, His-tagged E.coli His
    Mouse Il31-171M Recombinant Mouse Interleukin 31 E.coli N/A
    Mouse Il31-1923M Recombinant Mouse Il31 Protein E.coli N/A
    Mouse Il31-48M Recombinant Mouse Il31 protein, His-tagged HEK293 His
    Mouse IL31-8167M Recombinant Mouse IL31 Protein Mammalian Cell His
    Rat Il31-1574R Recombinant Rat Il31 protein, His & GST-tagged E.coli His/GST

    il31 involved in several pathways and played different roles in them. We selected most pathways il31 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with il31 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    il31 has several biochemical functions, for example, cytokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by il31 itself. We selected most functions il31 had, and list some proteins which have the same functions with il31. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity TIMP1; NODAL; CMTM3; KITLG; CXCL9; IL23; TNFSF13; IFNA3; IL7; FAM3B

    il31 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with il31 here. Most of them are supplied by our site. Hope this information will be useful for your research of il31.

    Yu, JI; Park, YR; et al. Polymorphisms of interleukin-31 are associated with anti-CCP levels in females with rheumatoid arthritis. JOURNAL OF GENETICS 93:813-817(2014).
    Maier, E; Werner, D; et al. Human Th2 but Not Th9 Cells Release IL-31 in a STAT6/NF-kappa B-Dependent Way. JOURNAL OF IMMUNOLOGY 193:645-654(2014).

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