IL31
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Official Full Name
interleukin 31
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Background
IL-31 is a cytokine with a four-helix bundle structure, which is preferentially produced by type 2 helper T cells (Th2). The structure of IL-31 places it in the IL-6 family of cytokines. IL-31 signals via a receptor complex that is composed of IL-31 receptor A (IL31RA) and oncostatin M receptor subunits. These receptor subunits are expressed in activated monocytes and in unstimulated epithelial cells. -
Synonyms
IL31; interleukin 31; interleukin-31; IL 31; IL-31;
- Involved Pathway
- Protein Function
- Interacting Protein
- IL31 Related Articles
- IL31 Related Gene Family
- IL31 Related Research Area
IL31 involved in several pathways and played different roles in them. We selected most pathways IL31 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with IL31 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
IL31 has several biochemical functions, for example, cytokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL31 itself. We selected most functions IL31 had, and list some proteins which have the same functions with IL31. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | NRG1;IFNA12;GREM1;NAMPT;GDF10B;IFNA6;CCL38A.5;FGF2;INHBAB |
IL31 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL31 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL31.
- Q&As
- Reviews
Q&As (6)
Ask a questionThe IL31 may have specificity for specific diseases, with relatively few side effects being a big advantage.
IL31 activates downstream signaling pathways by binding to receptors and participates in inflammatory response and immune regulation.
It has a wide range of applications in immune inflammation, dermatology and other research fields.
Clinical studies of IL31 are ongoing, but there is no clear therapeutic effect and effectiveness assessment at this time.
IL31 research still faces many challenges, including side effect evaluation, efficacy verification and other issues, and further efforts are needed.
Optimal dose may be related to individual differences, disease type and other factors, and the appropriate dose should be determined under the guidance of a doctor when using IL31.
Customer Reviews (3)
Write a reviewIt has the characteristics of high yield, high stability, high purity and strong adaptability, which provide a good basis for its clinical application. -
The structure of IL-31 is relatively stable and it is able to maintain its stability and activity under suitable storage conditions, which is very important for preservation and stability during production and use. -
Through proper expression and recombination techniques, the produced IL-31 has good biological activity and function, and can play the expected effect in clinical application. -
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