Recombinant Mouse Il33 Protein
Cat.No. : | Il33-3521M |
Product Overview : | Purified recombinant protein of Mouse interleukin 33 (Il33), transcript variant 2 without tag was expressed in E. coli. |
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Description : | In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets. This form is rapidely lost upon angiogenic or proinflammatory activation. |
Source : | E. coli |
Species : | Mouse |
Molecular Mass : | 17.6 kDa |
Protein length : | Ser109-Ile266 |
Endotoxin : | Less than 0.1 EU/μg (<0.01 ng/μg) protein as determined by the LAL method |
Purity : | > 98%, as determined by Coomassie stained SDS-PAGE. |
Stability : | Unopened vial can be stored between 2 and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | Protein formulated and vialed at >50 μg/mL in specified buffer |
Storage Buffer : | 20 mM HEPES, 150 mM NaCl, pH 7.2, 10 mM TCEP |
Gene Name : | Il33 interleukin 33 [ Mus musculus (house mouse) ] |
Official Symbol : | Il33 |
Synonyms : | Il33; interleukin 33; Il-; Il1f; NF-H; Il-33; Il1f11; NF-HEV; 9230117N10Rik; interleukin-33; nuclear factor from high endothelial venules |
Gene ID : | 77125 |
mRNA Refseq : | NM_133775 |
Protein Refseq : | NP_598536 |
UniProt ID : | Q8BVZ5 |
Products Types
◆ Recombinant Protein | ||
IL33-095I | Active Recombinant Human IL33 Protein (159 aa) | +Inquiry |
IL33-356I | Active Recombinant Human IL33 Protein (159 aa) | +Inquiry |
IL33-175M | Active Recombinant Mouse IL33 Protein | +Inquiry |
IL33-643D | Recombinant Dog IL33 protein(102-263aa), His-tagged | +Inquiry |
IL33-3829D | Recombinant Dog IL33 protein(102-263aa), His-tagged | +Inquiry |
◆ Lysates | ||
IL33-5226HCL | Recombinant Human IL33 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewGood solubility and is easy to operate and purify.
Effectively mimics the function of the target protein in vitro.
IL33 has a wide range of applications in the field of scientific research and is suitable for a variety of experimental design and research purposes.
Q&As (6)
Ask a questionIt can be used to detect immune cells such as macrophages and dendritic cells.
This protein applied in immunology, drug research, life science and other fields.
Regulates the activity of immune cells by binding to receptors to stimulate the production of inflammatory factors such as interferon and TNF-α.
IL33 can also be used to treat a variety of inflammatory diseases, such as inflammatory bowel disease, psoriasis and so on.
The preparation of IL33 requires first cloning the IL33 gene into the expression vector, and then the expression vector is expressed and purified in the cell culture medium.
Treating asthma with recombinant IL33 takes several weeks to several months to be effective, depending on the severity of the condition and the individual patient.
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