| Description : |
Involved in negative regulation of immune response. Acts upstream of or within negative regulation of apoptotic process; negative regulation of tolerance induction; and positive regulation of apoptotic process. Located in external side of plasma membrane. Is expressed in retina. Used to study dilated cardiomyopathy and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in autoimmune disease (multiple); hepatitis B; hepatitis C; hepatocellular carcinoma; and lupus nephritis. Orthologous to human PDCD1 (programmed cell death 1). |
| Source : |
HEK293 |
| Species : |
Mouse |
| Tag : |
Fc |
| Form : |
Lyophilized |
| Molecular Mass : |
43.2 kDa |
| Protein Length : |
288 |
| AA Sequence : |
MWVRQVPWSFTWAVLQLSWQSGWLL EVPNGPWRSLTFYPAWLTVSEGANA TFTCSLSNWSEDLMLNWNRLSPSNQ TEKQAAFCNGLSQPVQDARFQIIQL PNRHDFHMNILDTRRNDSGIYLCGA ISLHPKAKIEESPGAELVVTERILE TSTRYPSPSPKPEGRFQGMVIGIMS ALVGIPVLLLLAWALAVFCSTSMSE ARGAGSKDDTLKEEPSAAPVPSVAY EELDFQGREKTPELPTACVHTEYAT IVFTEGLGASAMGRRGSADGLQGPR PPRHEDGHCSWPL |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
