Recombinant Human PDCD1 Protein (Leu25-Gln167), C-hFc and 6×His-tagged
| Cat.No. : | PDCD1-687H |
| Product Overview : | Recombinant Human PDCD1 Protein (Leu25-Gln167) with C-hFc and 6×His tag was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
- Download
| Description : | This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | His&Fc |
| Form : | Lyophilized |
| Molecular Mass : | 42.9 kDa |
| Protein length : | Leu25-Gln167 |
| Purity : | > 90% as determined by SDS-PAGE and Coomassie blue staining. |
| Storage : | Store at -80 centigrade for 12 months (Avoid repeated freezing and thawing) |
| Storage Buffer : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 73 % trehalose is added as protectants before lyophilization. |
| Gene Name : | PDCD1 programmed cell death 1 [ Homo sapiens (human) ] |
| Official Symbol : | PDCD1 |
| Synonyms : | PDCD1; programmed cell death 1; programmed cell death protein 1; CD279; PD1; protein PD-1; PD-1; SLEB2; hPD-1; hPD-l; |
| Gene ID : | 5133 |
| mRNA Refseq : | NM_005018 |
| Protein Refseq : | NP_005009 |
| MIM : | 600244 |
| UniProt ID : | Q15116 |
Products Types
| ◆ Recombinant Protein | ||
| PDCD1-693C | Recombinant Cynomolgus monkey PDCD1 Protein, Fc-tagged | +Inquiry |
| PDCD1-370M | Active Recombinant Mouse PDCD1 Protein, Fc & Avi-tagged, Biotinylated | +Inquiry |
| PDCD1-356H | Recombinant Human PDCD1 protein, mFc-tagged | +Inquiry |
| PDCD1-1033R | Active Recombinant Rat PDCD1 protein(Met1-Gln167), hFc-tagged | +Inquiry |
| PDCD1-260H | Active Recombinant Human PDCD1 Protein, Fc-Avi-tagged, Biotinylated | +Inquiry |
Related Gene
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewTimely antibody validation, a valuable asset for our laboratory.
Precise protein quantification, fundamental for maintaining data accuracy.
Dependable peptide synthesis, accelerates our peptide-based projects effectively.
Q&As (14)
Ask a questionPDCD1 modulates responses to viral infections, affecting T cell function and viral clearance.
PDCD1 modulates responses to viral infections, affecting T cell function and viral clearance.
PDCD1 helps develop immune tolerance, preventing overactive immune responses.
PDCD1 maintains a balance between immune response and autoimmunity, preventing self-reactivity.
PDCD1 contributes to T cell exhaustion in chronic diseases and cancers, reducing immune efficacy.
PDCD1 maintains a balance between immune response and autoimmunity, preventing self-reactivity.
PDCD1's role in immunotherapy is pivotal, as blocking PD-1 enhances anti-tumor responses.
PDCD1 contributes to T cell exhaustion in chronic diseases and cancers, reducing immune efficacy.
PDCD1 regulates T cell activity by inhibiting immune responses, crucial in immune checkpoints.
PDCD1's role in immunotherapy is pivotal, as blocking PD-1 enhances anti-tumor responses.
PDCD1 helps develop immune tolerance, preventing overactive immune responses.
Changes in PDCD1 signaling impact autoimmune disease progression, influencing immune system activity.
PDCD1 regulates T cell activity by inhibiting immune responses, crucial in immune checkpoints.
Changes in PDCD1 signaling impact autoimmune disease progression, influencing immune system activity.
Ask a Question for All PDCD1 Products
Required fields are marked with *
My Review for All PDCD1 Products
Required fields are marked with *
Inquiry Basket
