Recombinant Human PDCD1 protein, Fc-Avi-tagged

• Cat.No.: PDCD1-116H
• Product Overview: Recombinant human PD1 is expressed from mammalian with a Fc tag and Avi Tag at the C-terminal. It contains Leu25-Gln167.

Specification

• Description: Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.
• Source: HEK293
• Species: Human
• Tag: Fc-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 44.7 kDa. Due to glycosylation, the protein migrates to 65-72 KD based on Bis-Tris PAGE result.
• Protein length: Leu25-Gln167
• Endotoxin: Less than 0.05 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: PDCD1
• Official Symbol: PDCD1
• Synonyms: hPD-1; PD-1; PD1hPD-1; PDCD1; CD279 antigen; CD279;programmed cell death 1; programmed cell death protein 1; Protein PD-1; SLEB2
• Gene ID: 5133
• mRNA Refseq: NM_005018.3
• Protein Refseq: NP_005009.2
• MIM: 600244
• UniProt ID: Q15116