Recombinant Rat Mitogen-activated Protein Kinase 8
| Cat.No. : | Mapk8-689R |
| Product Overview : | Recombinant rat Mapk8 is expressed inE. coli. |
- Specification
- Gene Information
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| Cat. No. : | Mapk8-689R |
| Description : | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. |
| Source : | E. coli. |
| Form : | Liquid. |
| Formulation : | In 150 mM NaCl, 50 mM Tris-HCl, 10 mM β-mercaptoethanol, 1 mM imidazole, 1 mM Mg (OAc) 2, 500 nM ATP, 10% glycerol, pH 7.5. |
| Molar Mass : | 48000Da. |
| Specific Activity : | ≥30 units/mg protein. |
| Unit Definition : | One unit is defined as the amount of enzyme that will phosphorylate 1.0 nmol GST-c-Jun (1-79) Substrate per min at 30°C, pH 7.5. |
| Purity : | ≥90% by SDS-PAGE. |
| Storage : | ≤ -70oC. Ship: Dry Ice Only. |
| Gene Name : | Mapk8 mitogen-activated protein kinase 8 [ Rattus norvegicus ] |
| Synonyms : | Mapk8; mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; SAPK gamma; c-Jun N-terminal kinase 1; c-jun NH2-terminal kinase; p54 gamma; stress-activated protein kinase JNK1; JNK |
| Gene ID : | 116554 |
| mRNA Refseq : | XM_341399 |
| Protein Refseq : | XP_341400 |
| UniProt ID : | P49185 |
| Chromosome Location : | 16p16 |
| Pathway : | ErbB signaling pathway; Fc epsilon RI signaling pathway; Focal adhesion; Insulin signaling pathway; NOD-like receptor signaling pathway; Neurotrophin signaling pathway; Progesterone-mediated oocyte maturation; Toll-like receptor signaling pathway; Wnt signaling pathway |
| Function : | ATP binding; JUN kinase activity; MAP kinase activity; protein serine/threonine kinase activity; transferase activity |
Products Types
| ◆ Recombinant Protein | ||
| Mapk8-3945M | Recombinant Mouse Mapk8 Protein, Myc/DDK-tagged | +Inquiry |
| MAPK8-1136H | Recombinant Human MAPK8 Protein (S2-E364), Tag Free | +Inquiry |
| MAPK8-2420H | Recombinant Human MAPK8 Protein, His-tagged | +Inquiry |
| MAPK8-3435H | Recombinant Human MAPK8 Protein, His (Fc)-Avi-tagged | +Inquiry |
| MAPK8-1137H | Recombinant Human MAPK8 Protein (S2-E364), His tagged | +Inquiry |
| ◆ Lysates | ||
| MAPK8-4489HCL | Recombinant Human MAPK8 293 Cell Lysate | +Inquiry |
| MAPK8-4488HCL | Recombinant Human MAPK8 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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