| Description : |
Predicted to enable several functions, including lipoprotein particle binding activity; lipoprotein particle receptor binding activity; and serine-type endopeptidase activity. Involved in several processes, including cellular response to insulin stimulus; cholesterol homeostasis; and protein autoprocessing. Located in extracellular space and rough endoplasmic reticulum. Human ortholog(s) of this gene implicated in familial hypercholesterolemia and hypobetalipoproteinemia. Orthologous to human PCSK9 (proprotein convertase subtilisin/kexin type 9). |
| Source : |
HEK293 |
| Species : |
Rat |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
73.2 kDa |
| Protein Length : |
691 |
| AA Sequence : |
MGIRCSTWLRWPLSPQLLLLLLLCP TGSRAQDEDGDYEELMLALPSQEDS LVDEASHVATATFRRCSKEAWRLPG TYVVVLMEETQRLQVEQTAHRLQTW AARRGYVIKVLHVFYDLFPGFLVKM SSDLLGLALKLPHVEYIEEDSLVFA QSIPWNLERIIPAWQQTEEDSSPDG SSQVEVYLLDTSIQSGHREIEGRVT ITDFNSVPEEDGTRFHRQASKCDSH GTHLAGVVSGRDAGVAKGTSLHSLR VLNCQGKGTVSGTLIGLEFIRKSQL IQPSGPLVVLLPLAGGYSRILNTAC QRLARTGVVLVAAAGNFRDDACLYS PASAPEVITVGATNAQDQPVTLGTL GTNFGRCVDLFAPGKDIIGASSDCS TCYMSQSGTSQAAAHVAGIVAMMLN RDPALTLAELRQRLILFSTKDVINM AWFPEDQRVLTPNRVATLPPSTQET GGQLLCRTVWSAHSGPTRTATATAR CAPEEELLSCSSFSRSGRRRGDRIE AIGGQQVCKALNAFGGEGVYAVARC CLLPRVNCSIHNTPAARAGPQTPVH CHQKDHVLTGCSFHWEVENLRAQQQ PLLRSRHQPGQCVGHQEASVHASCC HAPGLECKIKEHGIAGPAEQVTVAC EAGWTLTGCNVLPGASLPLGAYSVD NVCVARIRDAGRADRTSEEATVAAA ICCRSRPSAKASWVHQ |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
