Recombinant Rhesus monkey UGT1A1 Protein, His-tagged

• Cat.No.: UGT1A1-5099R
• Product Overview: Recombinant Rhesus monkey UGT1A1 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Rhesus monkey
• Tag: His
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: UGT1A1
• Synonyms: UGT1A1; UDP-glucuronosyltransferase 1-1; UDP-glucuronosyltransferase UGT1A01
• Gene ID: 574210
• mRNA Refseq: NM_001032869
• Protein Refseq: NP_001028041
• UniProt ID: Q95KM4

Reviews

08/12/2022

The product was kept in perfect condition and delivered on time so that I got the perfect product in the shortest time possible.

05/14/2022

Customer service contacted me in a timely manner and helped me solve a lot of problems that arose in my experiments.

Q&As

What is the function of UGT1A1?

UGT1A1 converts lipophilic small molecules, such as drugs, into water-soluble and excretable metabolites.

What is the relationship between bilirubin and UGT1A1?

Bilirubin is a binding substrate for UGT1A1 and UGT1A1 is involved in bilirubin metabolism.

What diseases is UGT1A1 involved in?

UGT1A1 is involved in lung cancer, colorectal cancer and hyperbilirubinemia, among other diseases.

Where is UGT1A1 mainly expressed?

UGT1A1 is mainly expressed in the liver.

What are the effects of mutations in the UGT1A1 gene?

Mutations in the UGT1A1 gene prevent the glucuronidation of free bilirubin and reduces bilirubin metabolism and increases serum free bilirubin levels.