alcam
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  • Official Full Name
  • activated leukocyte cell adhesion molecule
  • Background
  • This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
  • Synonyms
  • ALCAM; activated leukocyte cell adhesion molecule; MEMD; CD166; CD166 antigen; FLJ3851; FLJ38514; MGC71733
Cat.#:ALCAM-398HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human ALCAM Protein, Fc-tagged
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Cat.#:ALCAM-112HTag:T7|His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ALCAM protein, T7/His-tagged
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Cat.#:ALCAM-213HTag:Fc Chimera
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human ALCAM, Fc Chimera
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Cat.#:ALCAM-214HTag:Fc Chimera
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human ALCAM, Fc Chimera
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Cat.#:ALCAM-3140HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ALCAM, His tagged
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Cat.#:ALCAM-3241HTag:Fc|His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ALCAM, Fc-His tagged
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Cat.#:ALCAM-433HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ALCAM Protein, GST-tagged
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Cat.#:ALCAM-505HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ALCAM protein, His-tagged
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Cat.#:Alcam-1703MTag:Fc
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Alcam, Fc-tagged
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Cat.#:Alcam-232MTag:Fc Chimera
Source (Host):NSO cellsSpecies:Mouse
Product nameRecombinant Mouse Alcam, Fc Chimera
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Cat.#:Alcam-3267MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Alcam, His tagged
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Cat.#:Alcam-506MTag:His|T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Alcam protein, His & T7-tagged
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Cat.#:Alcam-624MTag:Fc|His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Alcam, Fc-His tagged
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Cat.#:Alcam-18RTag:Fc|His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Alcam, Fc tagged
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Cat.#:Alcam-507RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Alcam protein, His-tagged
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Cat.#:Alcam-7465RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Alcam, His tagged
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Cat.#:ALCAM-118CTag:N/A
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus ALCAM, His tagged
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Cat.#:ALCAM-1211CTag:Fc
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus ALCAM Protein, Fc-tagged
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Cat.#:ALCAM-300RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ALCAM Protein, His-tagged
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Cat.#:ALCAM-504DTag:His
Source (Host):E. coliSpecies:Dog
Product nameRecombinant Dog ALCAM protein, His-tagged
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Cat.#:ALCAM-508RTag:His
Source (Host):E. coliSpecies:Rabbit
Product nameRecombinant Rabbit ALCAM protein, His-tagged
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Cat.#:ALCAM-6734CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ALCAM
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Cat.#:ALCAM-503CTag:His
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle ALCAM protein, His-tagged
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Cat.#:ALCAM-2294HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human ALCAM cell lysate
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Cat.#:ALCAM-2644MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse ALCAM cell lysate
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Cat.#:ALCAM-828RCLTag:N/A
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat ALCAM cell lysate
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Cat.#:ALCAM-1098CCLTag:N/A
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus ALCAM cell lysate
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Involved Pathway

Alcam involved in several pathways and played different roles in them. We selected most pathways Alcam participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with Alcam were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell adhesion molecules (CAMs)
HLA-DRB5; NRXN3; CLDN15LB; PTPRM; CD58; CADM1A; CLDN15LA; NRXN2; Icosl; H2-AB1

Protein Function

Alcam has several biochemical functions, for example, protein binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Alcam itself. We selected most functions Alcam had, and list some proteins which have the same functions with Alcam. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein SNX31; FAH; FURIN; RAD23A; TUBA3C; SLBP; TECPR1; UHMK1; EXOSC10; TNFRSF21
Function receptor binding
Related Protein CXADR; GRIN2A; DAO1; IAPP; ABCA1; ECI2; SCP2; MPV17L; INSL4; FGF13B

Interacting Protein

Alcam has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Alcam here. Most of them are supplied by our site. Hope this information will be useful for your research of Alcam.
LGALS1; LGALS3; CD6; ART3; EGFR

Alcam Related Articles

Williams, DW; Anastos, K; et al. JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14(+)CD16(+) monocytes in HIV-infected individuals. JOURNAL OF LEUKOCYTE BIOLOGY 97:401-412(2015).
Ding, V; Chin, A; et al. Generation of novel monoclonal antibodies for the enrichment and characterization of human corneal endothelial cells (hCENC) necessary for the treatment of corneal endothelial blindness. MABS 6:1439-1452(2014).