becn1
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  • Official Full Name
  • beclin 1, autophagy related
  • Background
  • Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration
  • Synonyms
  • BECN1; beclin 1, autophagy related; ATG6; VPS30; beclin1; beclin 1 (coiled-coil, moesin-like BCL2 interacting protein); ATG6 autophagy related 6 homolog (S. cerevisiae); Beclin-1; Coiled-coil myosin-like BCL2-interacting protein; Protein GT197; GT197; ATG6 autophagy related 6 homolog; ATG6; VPS30; beclin1; Bcl-2-interacting protein beclin
Cat.#:BECN1-2059MTag:His-SUMO
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse BECN1 Protein (1-448 aa), His-SUMO-tagged
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Cat.#:BECN1-10203HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BECN1, GST-tagged
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Cat.#:BECN1-189HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BECN1 Protein, GST-tagged
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Cat.#:BECN1-190HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BECN1 Protein, GST-tagged
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Cat.#:BECN1-294HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BECN1 protein, His/MBP-tagged
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Cat.#:BECN1-295HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BECN1 protein, His/MBP-tagged
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Cat.#:BECN1-296HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BECN1 protein, His/MBP-tagged
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Cat.#:BECN1-377HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human beclin 1, autophagy related, His-tagged
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Cat.#:BECN1-2370MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse BECN1 Protein
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Cat.#:BECN1-967RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat BECN1 Protein
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Cat.#:BECN1-529RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey BECN1 Protein, His-tagged
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Cat.#:BECN1-1476CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken BECN1
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Cat.#:BECN1-11120ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish BECN1
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Cat.#:BECN1-8470HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human BECN1 293 Cell Lysate
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Involved Pathway

BECN1 involved in several pathways and played different roles in them. We selected most pathways BECN1 participated on our site, such as Regulation of autophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with BECN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Regulation of autophagy
ATG4A; ATG16L1; INS2; Ifna15; IFNA3; INS1; GABARAP; PIK3C3; INSB; INS

Protein Function

BECN1 has several biochemical functions, for example, phosphatidylinositol 3-kinase binding, protein binding, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BECN1 itself. We selected most functions BECN1 had, and list some proteins which have the same functions with BECN1. You can find most of the proteins on our site.
Function
Related Protein
Function phosphatidylinositol 3-kinase binding
Related Protein FLT3; IGF1RA; CALM1; TYRO3; JAK2; PDGFRB; FYN; IRS1; LCK; CALM3
Function protein binding
Related Protein HDDC3; MLLT1; GPRASP1; SEC61G; HAT1; MYLIP; RABIF; FCRL2; TMEM93; FAM123A
Function ubiquitin protein ligase binding
Related Protein TRAF5; MOAP1; NKD2; ANKRD32; MAGEA2; SLC22A18; WFS1; UBE2KB; ATXN3; SPOP

Interacting Protein

BECN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BECN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BECN1.
ATG14