|Official Full Name||BH3 interacting domain death agonist|
|Background||This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]|
|Synonyms||BID; BH3 interacting domain death agonist; FP497; BH3-interacting domain death agonist; p22 BID; BID isoform Si6; BID isoform L(2); BID isoform ES(1b); desmocollin type 4; apoptic death agonist; Human BID coding sequence;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
BID involved in several pathways and played different roles in them. We selected most pathways BID participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with BID were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Sphingolipid signaling pathway||PIK3CB; PLD1; MAP2K1; S1PR5; PRKCG; NRAS; PLCB3; LOC100328615; OPRD1; GAB2|
|p signaling pathway||LRDD; CD82A; SHISA5; CCNB3; Casp3; TSC2; THBS1; EI24; PPM1DB; RPRM|
|Apoptosis||RIPK1; FASLG; DNM1L; PPP3CCA; HELLS; PIK3CB; PIK3CD; CASP7; STK26; PIK3CA|
|Natural killer cell mediated cytotoxicity||PIK3R2; KLRC2; TNF; ICAM1; FASLG; HLA-C; SAMD3; PIK3R5; Raet1c; ITGAL|
|Non-alcoholic fatty liver disease (NAFLD)||CASP8; CEBPA; RAC1; MAP3K11; NDUFB6; COX4I2; NDUFB11; RXRA; NDUFA12; PIK3CD|
|Alzheimers disease||APBB1; FADD; TNFRSF1A; NDUFS6; SDHB; COX5A; UQCRFS1; CALML3; GRIN2B; APOE|
|Amyotrophic lateral sclerosis (ALS)||DERL1; GRIN2A; GRIA1; GRIN1; BCL2L1; PPP3R1; BCL2; MAP2K6; SLC1A2; BID|
|Tuberculosis||RFXAP; IL10RB; CARD9; Ifna15; IFNGR2; HSPA9; ATP6V0A1; PIK3C3; FCGR2C; IL10RA|
|Pathways in cancer||GNAI2; PRKACA; FGFR3; GNB1; ARHGEF1; TRP53; MECOM; FGF6; RARA; TRAF6|
|Viral myocarditis||CASP8; ACTB; CCND1; SGCA; RAC1; EIF4G2; CASP9; HLA-DQA1; ACTG1; HLA-DPB1|
BID has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by BID itself. We selected most functions BID had, and list some proteins which have the same functions with BID. You can find most of the proteins on our site.
|death receptor binding||TMBIM1; TNFSF15; MYD88; Casp3; Fasl; FASLG; CASP8; RIPK1; FEM1B; CFLAR|
|protein binding||TLR3; EMP3; NIPAL3; USP13; ANXA2; SPG7; LMO3; DPM1; SIRT7; MCPH1|
|ubiquitin protein ligase binding||CUL9; VCL; SUMO2; Fzd4; TSG101; UBE2W; SQSTM1; STX8; UBXN1; FOXO1|
BID has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BID here. Most of them are supplied by our site. Hope this information will be useful for your research of BID.
BCL2; BCL2L1; BAX