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  • Official Full Name
  • BH3 interacting domain death agonist
  • Background
  • This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
  • Synonyms
  • BID; BH3 interacting domain death agonist; FP497; BH3-interacting domain death agonist; p22 BID; BID isoform Si6; BID isoform L(2); BID isoform ES(1b); desmocollin type 4; apoptic death agonist; Human BID coding sequence;
Cat.#:BID-2006HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BID Protein, His-tagged
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Cat.#:BID-218HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BID Protein, GST-tagged
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Cat.#:BID-26710THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BID
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Cat.#:BID-26711THTag:
Source (Host):Species:Human
Product nameRecombinant Human BID
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Cat.#:BID-3838HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BID, None tagged
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Cat.#:BID-6977HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human BID, GST-tagged
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Cat.#:BID-2404MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse BID Protein
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Cat.#:Bid-258MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Bid
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Cat.#:Bid-4029MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Bid, His & GST tagged
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Cat.#:Bid-633RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Bid protein, His & T7-tagged
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Cat.#:BID-6121CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken BID
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Cat.#:BID-1437HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human BH3 Interacting Domain Death Agonist,GST-tagged
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Cat.#:BID-2427HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BH3 Interacting Domain Death Agonist, His-tagged
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Cat.#:BID-380HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BH3 Interacting Domain Death Agonist
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Cat.#:Bid-1382MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse BH3 Interacting Domain Death Agonist
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Cat.#:Bid-1383MTag:GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse BH3 Interacting Domain Death Agonist, GST-tagged
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Cat.#:Bid-1384MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse BH3 Interacting Domain Death Agonist, 61-195aa
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Cat.#:BID-8455HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human BID 293 Cell Lysate
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Cat.#:BID-8456HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human BID 293 Cell Lysate
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Involved Pathway

BID involved in several pathways and played different roles in them. We selected most pathways BID participated on our site, such as Sphingolipid signaling pathway, p signaling pathway, Apoptosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with BID were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Sphingolipid signaling pathway
PRKCB; SPHK1; PLD1; PPP2R5D; PRKCA; PPP2R3A; SGMS1; GNAI3; PRKCG; ASAH1
p signaling pathway
SERPINE1; CCNE2; GADD45AA; TP53; BAI1; SIAH2L; FAS; CCND2; CCND2A; MDM4
Apoptosis
BIRC3; TNFRSF10C; IRF1B; CAPN1A; CASP3A; DSG3; GZME; NFKBIAA; IL1R1; PRKACBB
Natural killer cell mediated cytotoxicity
IFNA2; KIR2DS5; TNFRSF10A; SHC1; GM-CSF; VAV2; PPP3CC; PRKCA; CD244; KRAS
Non-alcoholic fatty liver disease (NAFLD)
COX7A1; COX8C; Casp3; LEPR; RXRA; NFKB1; NDUFS4; TNFRSF1A; NDUFA4; NDUFB5
Alzheimers disease
NDUFV1; CDK5R1; NDUFB8; HSD17B10; NDUFS5; CAPN1; UQCRC2; NDUFS6; NDUFS7; NDUFB6
Amyotrophic lateral sclerosis (ALS)
BAX; TNFRSF1A; PPP3R1; GRIA2; CASP12; CYCS; MAP2K6; GRIA1; PPP3R2; MAPK13
Tuberculosis
IRAK2; CLEC4M; IRAK4; SRC; HLA-DQB1; MYD88; CD209C; MAPK13; IFNA10; TLR1
Pathways in cancer
MAX; BIRC2; HIF1A; ARNT2; GLI3; PDGFA; PPARG; GNB1; TRAF3; GNAQ
Viral myocarditis
CD80; HLA-DRA; RAC3; H2-AB1; SGCB; CYCS; RAC2; CD40LG; HLA-A; ACTG1

Protein Function

BID has several biochemical functions, for example, death receptor binding, protein binding, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BID itself. We selected most functions BID had, and list some proteins which have the same functions with BID. You can find most of the proteins on our site.
Function
Related Protein
Function death receptor binding
Related Protein TNFSF15; RIPK1; FASLG; PIDD1; MYD88; TMBIM1; NOL3; PRDM4; BID; FADD
Function protein binding
Related Protein HSPB1; SIAH2; CALCOCO2; PPIE; UCN; SULT2A1; SVIP; TGFBR1; SLC9A7; MORN2
Function ubiquitin protein ligase binding
Related Protein TNFRSF14; UBE2H; UBE2Z; TPI1; LRPPRC; TRIOBP; UBE2NB; PIAS1; FZD5; RANGAP1

Interacting Protein

BID has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BID here. Most of them are supplied by our site. Hope this information will be useful for your research of BID.
BCL2; BCL2L1; BAX

BID Related Articles

Chandran, SR; Tesch, GH; et al. Spleen tyrosine kinase contributes to acute renal allograft rejection in the rat. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY 96:54-62(2015).
Singh, SV; Singh, PK; et al. Evaluation of goat based 'Indigenous vaccine' against Bovine Johne's Disease in endemically infected native cattle herds. INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY 53:16-24(2015).

BID Related Gene Family

BCL2 Gene Family