BID

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BID

Official Full Name BH3 interacting domain death agonist
Background This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
Synonyms BID; BH3 interacting domain death agonist; FP497; BH3-interacting domain death agonist; p22 BID; BID isoform Si6; BID isoform L(2); BID isoform ES(1b); desmocollin type 4; apoptic death agonist; Human BID coding sequence;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BID-2006H Recombinant Human BID Protein, His-tagged E.coli His
    Human BID-1437H Recombinant Human BH3 Interacting Domain Death Agonist,GST-tagged Sf9 Insect Cell GST
    Human BID-218H Recombinant Human BID Protein, GST-tagged Wheat Germ GST
    Human BID-2427H Recombinant Human BH3 Interacting Domain Death Agonist, His-tagged E.coli His
    Human BID-26710TH Recombinant Human BID E.coli N/A
    Human BID-26711TH Recombinant Human BID N/A
    Human BID-380H Recombinant Human BH3 Interacting Domain Death Agonist E.coli N/A
    Human BID-3838H Recombinant Human BID, None tagged E.coli N/A
    Human BID-6977H Recombinant Human BID, GST-tagged Sf9 Insect Cell GST
    Human BID-8455HCL Recombinant Human BID 293 Cell Lysate HEK293 N/A
    Human BID-8456HCL Recombinant Human BID 293 Cell Lysate HEK293 N/A
    Mouse Bid-1382M Recombinant Mouse BH3 Interacting Domain Death Agonist E.coli N/A
    Mouse Bid-1383M Recombinant Mouse BH3 Interacting Domain Death Agonist, GST-tagged E.coli GST
    Mouse Bid-1384M Recombinant Mouse BH3 Interacting Domain Death Agonist, 61-195aa E.coli N/A
    Mouse BID-2404M Recombinant Mouse BID Protein Mammalian Cell His
    Mouse Bid-258M Recombinant Mouse Bid E.coli N/A
    Mouse Bid-4029M Recombinant Mouse Bid, His & GST tagged E.coli His/GST
    Rat Bid-633R Recombinant Rat Bid protein, His & T7-tagged E.coli His/T7
    Chicken BID-6121C Recombinant Chicken BID Mammalian Cell His

    BID involved in several pathways and played different roles in them. We selected most pathways BID participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with BID were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Sphingolipid signaling pathway PIK3CB; PLD1; MAP2K1; S1PR5; PRKCG; NRAS; PLCB3; LOC100328615; OPRD1; GAB2
    p signaling pathway LRDD; CD82A; SHISA5; CCNB3; Casp3; TSC2; THBS1; EI24; PPM1DB; RPRM
    Apoptosis RIPK1; FASLG; DNM1L; PPP3CCA; HELLS; PIK3CB; PIK3CD; CASP7; STK26; PIK3CA
    Natural killer cell mediated cytotoxicity PIK3R2; KLRC2; TNF; ICAM1; FASLG; HLA-C; SAMD3; PIK3R5; Raet1c; ITGAL
    Non-alcoholic fatty liver disease (NAFLD) CASP8; CEBPA; RAC1; MAP3K11; NDUFB6; COX4I2; NDUFB11; RXRA; NDUFA12; PIK3CD
    Alzheimers disease APBB1; FADD; TNFRSF1A; NDUFS6; SDHB; COX5A; UQCRFS1; CALML3; GRIN2B; APOE
    Amyotrophic lateral sclerosis (ALS) DERL1; GRIN2A; GRIA1; GRIN1; BCL2L1; PPP3R1; BCL2; MAP2K6; SLC1A2; BID
    Tuberculosis RFXAP; IL10RB; CARD9; Ifna15; IFNGR2; HSPA9; ATP6V0A1; PIK3C3; FCGR2C; IL10RA
    Pathways in cancer GNAI2; PRKACA; FGFR3; GNB1; ARHGEF1; TRP53; MECOM; FGF6; RARA; TRAF6
    Viral myocarditis CASP8; ACTB; CCND1; SGCA; RAC1; EIF4G2; CASP9; HLA-DQA1; ACTG1; HLA-DPB1

    BID has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by BID itself. We selected most functions BID had, and list some proteins which have the same functions with BID. You can find most of the proteins on our site.

    Function Related Protein
    death receptor binding TMBIM1; TNFSF15; MYD88; Casp3; Fasl; FASLG; CASP8; RIPK1; FEM1B; CFLAR
    protein binding TLR3; EMP3; NIPAL3; USP13; ANXA2; SPG7; LMO3; DPM1; SIRT7; MCPH1
    ubiquitin protein ligase binding CUL9; VCL; SUMO2; Fzd4; TSG101; UBE2W; SQSTM1; STX8; UBXN1; FOXO1

    BID has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BID here. Most of them are supplied by our site. Hope this information will be useful for your research of BID.

    BCL2; BCL2L1; BAX

    Chandran, SR; Tesch, GH; et al. Spleen tyrosine kinase contributes to acute renal allograft rejection in the rat. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY 96:54-62(2015).
    Singh, SV; Singh, PK; et al. Evaluation of goat based 'Indigenous vaccine' against Bovine Johne's Disease in endemically infected native cattle herds. INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY 53:16-24(2015).

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