Recombinant Mouse BH3 Interacting Domain Death Agonist, 61-195aa
Cat.No. : | Bid-1384M |
Product Overview : | Truncated BID Mouse Recombinant also called BH3-interacting domain death agonist p15 produced inE.Coliis a single, non-glycosylated polypeptide chain containing 61-195 amino acids (135 a.a.) and having a molecular mass of 15.4 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Bid-1384M |
Description : | Truncated BH3 interacting domain death agonist is a truncated form of the pro-apoptotic full-length BID. Truncated BH3 interacting domain death agonist is generated by Caspase-8 cleavage of BID. The truncated form of the protein translocates from the cytosol to mitochondria and transduces apoptotic signals. Bax induces the opening of the mitochondrial voltage-dependent anion channel which lead to the release of cytochrome c and other pro-apoptotic factors from the mitochondria resulting in activation of caspases. CASP8 cleaves BID, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. |
Source : | Escherichia Coli. |
Physical Appearance : | Sterile Filtered colorless liquid formulation. |
Formulation : | The Mouse Truncated BID protein solution contains 10mM Tris-HCL pH-8, 1mM EDTA and 250mM NaCl. |
Purity : | Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
Stability : | TBID although stable at 15°C for 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
Gene Name : | Bid BH3 interacting domain death agonist [ Mus musculus ] |
Synonyms : | Bid; BH3 interacting domain death agonist; AI875481; AU022477; 2700049M22Rik; OTTMUSP00000028756 |
Gene ID : | 12122 |
mRNA Refseq : | NM_007544 |
Protein Refseq : | NP_031570 |
UniProt ID : | P70444 |
Chromosome Location : | 6 F1; 6 54.0 cM |
Pathway : | Alzheimer"s disease; Amyotrophic lateral sclerosis (ALS); Natural killer cell mediated cytotoxicity; Pathways in cancer; p53 signaling pathway |
Function : | protein binding |
Products Types
◆ Recombinant Protein | ||
Bid-4029M | Active Recombinant Mouse Bid protein(Met1-Asp195), His&GST-tagged | +Inquiry |
BID-2006H | Recombinant Human BID Protein, His-tagged | +Inquiry |
Bid-711M | Recombinant Mouse Bid Protein, MYC/DDK-tagged | +Inquiry |
BID-1032M | Recombinant Mouse BID Protein, His (Fc)-Avi-tagged | +Inquiry |
Bid-633R | Recombinant Rat Bid protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
BID-8456HCL | Recombinant Human BID 293 Cell Lysate | +Inquiry |
BID-8455HCL | Recombinant Human BID 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket