Recombinant Human BID Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: BID-1625H
• Product Overview: BID MS Standard C13 and N15-labeled recombinant protein (NP_001187) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2, and thus regulate apoptosis. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 26.8 kDa
• AA Sequence: MCSGAGVMMARWAARGRAGWRSTVR ILSPLGHCEPGVSRSCRAAQAMDCE VNNGSSLRDECITNLLVFGFLQSCS DNSFRRELDALGHELPVLAPQWEGY DELQTDGNRSSHSRLGRIEADSESQ EDIIRNIARHLAQVGDSMDRSIPPG LVNGLALQLRNTSRSEEDRNRDLAT ALEQLLQAYPRDMEKEKTMLVLALL LAKKVASQTPSLLRDVFHTTVNFIN QNLRTYVRSLARNGMDTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: BID BH3 interacting domain death agonist [ Homo sapiens (human) ]
• Official Symbol: BID
• Synonyms: BID; BH3 interacting domain death agonist; BH3-interacting domain death agonist; p22 BID; BID isoform Si6; BID isoform L(2); BID isoform ES(1b); desmocollin type 4; apoptic death agonist; Human BID coding sequence; FP497; MGC15319; MGC42355
• Gene ID: 637
• mRNA Refseq: NM_001196
• Protein Refseq: NP_001187
• MIM: 601997
• UniProt ID: P55957