|Official Full Name||complement component 1, q subcomponent, alpha polypeptide|
|Background||C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.|
|Synonyms||C1QA; complement component 1, q subcomponent, alpha polypeptide; C1q; AI255395; complement C1q subcomponent subunit A;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
C1QA involved in several pathways and played different roles in them. We selected most pathways C1QA participated on our site, such as Complement and coagulation cascades, Prion diseases, Pertussis, which may be useful for your reference. Also, other proteins which involved in the same pathway with C1QA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Complement and coagulation cascades||PLAUR; F12; SERPINA5; TFPI; F13A1; BDKRB2; F5; C1RA; FGA; PLAT|
|Prion diseases||C9; C1QB; STIP1; PRNP; C6; MAPK3; HSPA5; ELK1; LOC100033925; MAP2K2|
|Pertussis||NFKB1; Hc; ITGB1; CASP1; C2; GNAI2; TICAM2; IL12A; ITGA5; MAPK3|
|Chagas disease (American trypanosomiasis)||PIK3R5; GNAI2; GNAI3; PLCB1; GNAO1; IRAK4; PIK3R3; MAPK9; TRAF6; PLCB3|
|Staphylococcus aureus infection||FCGR1A; HLA-DPB1; C4A; C1R; CFI; ITGAM; HLA-DOA; C1QA; Hc; HLA-DQA2|
|Systemic lupus erythematosus||HIST1H2BB; H2BFWT; HIST1H2BG; HIST1H3E; FCGR3B; HLA-DRA; ACTN2; CD80; C1S; ELANE|
C1QA has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C1QA itself. We selected most functions C1QA had, and list some proteins which have the same functions with C1QA. You can find most of the proteins on our site.
|protein binding||ADD1; TARDBP; XRCC3; GINS4; ZBTB7B; SNRPG; MRPS27; DUSP2; SH2D4A; WAS|
C1QA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C1QA here. Most of them are supplied by our site. Hope this information will be useful for your research of C1QA.
C1QB; C1QC; LRP1; SGTA; PIAS2; PPP1CC; BAG6; PPP1CA; SLC25A47; GNPNAT1; HIPK3; q9k5j5_bacan; UBQLN2; UBQLN1; APOA1