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Official Full Name complement component 1, q subcomponent, alpha polypeptide
Background C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Synonyms C1QA; complement component 1, q subcomponent, alpha polypeptide; C1q; AI255395; complement C1q subcomponent subunit A;
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human
    • Human Serum
    • Mammalian Cell
    • Yeast
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human C1QA-926H Recombinant human C1QA protein, His-tagged E.coli His
    Mouse C1QA-1345M Recombinant Mouse C1QA Protein (23-245 aa), His-tagged Yeast His
    Human C1QA-10475H Recombinant Human C1QA, GST-tagged E.coli GST
    Human C1QA-26126TH Native Human C1QA Human Serum N/A
    Human C1QA-4292H Recombinant Human Complement Component 1, q Subcomponent, A Chain Human N/A
    Human C1QA-8143HCL Recombinant Human C1QA 293 Cell Lysate HEK293 N/A
    Human C1QA-925H Recombinant Human C1QA Protein, His-tagged E.coli His
    Mouse C1QA-2560M Recombinant Mouse C1QA Protein Mammalian Cell His
    Mouse C1qa-7932M Recombinant Mouse C1qa protein, His & T7-tagged E.coli His/T7
    Rat C1QA-1041R Recombinant Rat C1QA Protein Mammalian Cell His
    Rat C1qa-7933R Recombinant Rat C1qa protein, His & T7-tagged E.coli His/T7
    Zebrafish C1QA-2722Z Recombinant Zebrafish C1QA Mammalian Cell His

    C1QA involved in several pathways and played different roles in them. We selected most pathways C1QA participated on our site, such as Complement and coagulation cascades, Prion diseases, Pertussis, which may be useful for your reference. Also, other proteins which involved in the same pathway with C1QA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Complement and coagulation cascades PLAUR; F12; SERPINA5; TFPI; F13A1; BDKRB2; F5; C1RA; FGA; PLAT
    Prion diseases C9; C1QB; STIP1; PRNP; C6; MAPK3; HSPA5; ELK1; LOC100033925; MAP2K2
    Pertussis NFKB1; Hc; ITGB1; CASP1; C2; GNAI2; TICAM2; IL12A; ITGA5; MAPK3
    Chagas disease (American trypanosomiasis) PIK3R5; GNAI2; GNAI3; PLCB1; GNAO1; IRAK4; PIK3R3; MAPK9; TRAF6; PLCB3
    Staphylococcus aureus infection FCGR1A; HLA-DPB1; C4A; C1R; CFI; ITGAM; HLA-DOA; C1QA; Hc; HLA-DQA2
    Systemic lupus erythematosus HIST1H2BB; H2BFWT; HIST1H2BG; HIST1H3E; FCGR3B; HLA-DRA; ACTN2; CD80; C1S; ELANE

    C1QA has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C1QA itself. We selected most functions C1QA had, and list some proteins which have the same functions with C1QA. You can find most of the proteins on our site.

    Function Related Protein
    protein binding ADD1; TARDBP; XRCC3; GINS4; ZBTB7B; SNRPG; MRPS27; DUSP2; SH2D4A; WAS

    C1QA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C1QA here. Most of them are supplied by our site. Hope this information will be useful for your research of C1QA.

    C1QB; C1QC; LRP1; SGTA; PIAS2; PPP1CC; BAG6; PPP1CA; SLC25A47; GNPNAT1; HIPK3; q9k5j5_bacan; UBQLN2; UBQLN1; APOA1

    Yuan, HY; Chen, R; et al. Crystallization and preliminary crystallographic studies of the complement 1qA globular domain from zebrafish, Dare-C1qAgD. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS 70:911-914(2014).
    Trouw, LA; Daha, N; et al. Genetic variants in the region of the C1q genes are associated with rheumatoid arthritis. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 173:76-83(2013).

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