Recombinant human C1QA protein, His-tagged
Cat.No. : | C1QA-926H |
Product Overview : | Recombinant C1QA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the A-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. Alternate splicing results in multiple transcript variants. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Molecular Mass : | 30 kDa |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | C1QA |
Official Symbol : | C1QA |
Synonyms : | C1QA |
Gene ID : | 712 |
mRNA Refseq : | NM_015991.4 |
Protein Refseq : | NP_057075.1 |
MIM : | 120550 |
UniProt ID : | P02745 |
Products Types
◆ Recombinant Protein | ||
C1QA-1131M | Recombinant Mouse C1QA Protein, His (Fc)-Avi-tagged | +Inquiry |
C1QA-699R | Recombinant Rat C1QA Protein, His (Fc)-Avi-tagged | +Inquiry |
C1QA-2528H | Recombinant Human C1QA protein(23-245 aa), C-His-tagged | +Inquiry |
C1QA-1345M | Recombinant Mouse C1QA Protein (23-245 aa), His-tagged | +Inquiry |
C1QA-333H | Recombinant Human C1QA Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
C1QA-26126TH | Native Human C1QA | +Inquiry |
◆ Lysates | ||
C1QA-8143HCL | Recombinant Human C1QA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionIt plays a role in recognizing and promoting the removal of apoptotic cells.
Strategies are being explored to modulate C1QA activity in conditions like lupus and rheumatoid arthritis.
Genetic deficiencies in C1QA are linked to increased susceptibility to infections and autoimmune conditions.
C1QA is involved in immune responses against pathogens and in the clearance of immune complexes.
Dysregulation of C1QA can contribute to impaired clearance of immune complexes, leading to autoimmune diseases.
It binds to antibodies or C-reactive protein on pathogen surfaces, activating C1r and C1s in the C1 complex.
C1QA is a vital component of the C1 complex, initiating the classical complement pathway.
Customer Reviews (3)
Write a reviewExcellent quality, fast delivery.
Reliable in experiments, quality.
Product met all requirements.
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