ca12
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  • Official Full Name
  • carbonic anhydrase XII
  • Background
  • Carbonic anhydrases (CA) are a family of ancient zinc metalloenzymes found in almost all living organisms. All CA can be divided into 3 distinct classes (alpha, beta, and gamma) that evolved independently and have no significant homology in sequence and o
  • Synonyms
  • CA12; carbonic anhydrase XII; carbonic anhydrase 12; HsT18816; CA-XII; carbonic dehydratase; carbonate dehydratase XII; tumor antigen HOM-RCC-3.1.3; CAXII; FLJ20151; CAR12; carbonic anyhydrase 12; CA XII; AI314958; 2310047E01Rik
Cat.#:CA12-0233HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CA12 Protein, GST-Tagged
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Cat.#:CA12-2032HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CA12 Protein, MYC/DDK-tagged
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Cat.#:CA12-104HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CA12, His-tagged
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Cat.#:CA12-10615HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CA12, GST-tagged
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Cat.#:CA12-261HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CA12, His tagged
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Cat.#:CA12-26248THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CA12
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Cat.#:CA12-7846HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CA12 protein, His-tagged
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Cat.#:CA12-805HTag:
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human CA12 Protein
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Cat.#:CA12-971HTag:His
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human CA12 Protein, His-tagged
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Cat.#:CA12-260MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CA12, His tagged
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Cat.#:CAR12-2714MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CAR12 Protein
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Cat.#:CA12-595RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CA12 Protein, His-tagged
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Cat.#:CA12-3061HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CA12 cell lysate
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Cat.#:CA12-3067MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CA12 cell lysate
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Involved Pathway

CA12 involved in several pathways and played different roles in them. We selected most pathways CA12 participated on our site, such as Nitrogen metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CA12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Nitrogen metabolism
GLUL; CAR13; GLULB; CA12; CA9; GLULC; CAR6; CA5A; Car9; CA13

Protein Function

CA12 has several biochemical functions, for example, carbonate dehydratase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CA12 itself. We selected most functions CA12 had, and list some proteins which have the same functions with CA12. You can find most of the proteins on our site.
Function
Related Protein
Function carbonate dehydratase activity
Related Protein CAR7; Car14; CA5B; CA13; CAR13; CA15C; Car12; CA14; Car9; CAR6
Function zinc ion binding
Related Protein ZCCHC18; ACE2; HNF4A; ZNF185; MKRN4; S100A5; MAP3K7IP3; GATA2; FTR72; MORC3

Interacting Protein

CA12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CA12 here. Most of them are supplied by our site. Hope this information will be useful for your research of CA12.
SGSM2; ATP5C1; CUX1; LGALS7B; MAPK6; RDH11; TOE1; MRPL9; KATNBL1; DAXX

CA12 Related Articles

Pogue-Geile, KL; Kim, C; et al. Predicting Degree of Benefit From Adjuvant Trastuzumab in NSABP Trial B-31. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE 105:1782-1788(2013).
Wilbur, DS; Chyan, MK; et al. Reagents for Astatination of Biomolecules. 6. An Intact Antibody Conjugated with a Maleimido-closo-Decaborate(2-) Reagent via Sulfhydryl Groups Had Considerably Higher Kidney Concentrations than the Same Antibody Conjugated with an Isothiocyanato-closo-Decaborate(2-) Reagent via Lysine Amines. BIOCONJUGATE CHEMISTRY 23:409-420(2012).