ccl8
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  • Official Full Name
  • chemokine (C-C motif) ligand 8
  • Background
  • Monocyte chemotactic protein-2 (MCP-2); is a non-glycosylated polypeptide that is a member of the C-C chemokine subfamily and it specifically attracts monocytes, lymphocytes, basophils and eosinophils. It also plays a role in neoplasia and inflammatory ho
  • Synonyms
  • CCL8; chemokine (C-C motif) ligand 8; SCYA8, small inducible cytokine subfamily A (Cys Cys), member 8 (monocyte chemotactic protein 2); C-C motif chemokine 8; HC14; MCP 2; small-inducible cytokine A8; monocyte chemotactic protein 2; monocyte chemoattract
Cat.#:CCL8-313HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human CCL8 Protein, His-tagged
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Cat.#:CCL8-284HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Chemokine (C-C Motif) Ligand 8
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Cat.#:Ccl8-285MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Chemokine (C-C Motif) Ligand 8
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Cat.#:CCL8-031HTag:His
Source (Host):HEK293 cellSpecies:Human
Product nameRecombinant Human CCL8 Protein, His-tagged
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Cat.#:CCL8-032HTag:DDK
Source (Host):HEK293 cellSpecies:Human
Product nameRecombinant Human CCL8 Protein, DDK-tagged
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Cat.#:CCL8-198HTag:SUMO
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCL8, SUMO tagged
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Cat.#:CCL8-28723THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCL8
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Cat.#:CCL8-302HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Chemokine (C-C Motif) Ligand 8, HIgG1 Fc-tagged, mutant
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Cat.#:CCL8-303HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Chemokine (C-C Motif) Ligand 8, MIgG2a Fc-tagged
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Cat.#:CCL8-304HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Chemokine (C-C Motif) Ligand 8, HIgG1 Fc-tagged
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Cat.#:CCL8-693HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCL8 protein, His & T7-tagged
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Cat.#:Ccl8-10854mTag:GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant mouse Ccl8, GST-tagged
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Cat.#:Ccl8-202MTag:His/NusA
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ccl8, His & NusA tagged
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Cat.#:Ccl8-694MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ccl8 protein, His & T7-tagged
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Cat.#:CCL8-694RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CCL8 Protein, His-tagged
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Cat.#:CCL8-692CTag:His/GST
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle CCL8 protein, His & GST-tagged
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Cat.#:CCL8-695PTag:His/GST
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig CCL8 protein, His & GST-tagged
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Cat.#:Ccl8-100MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Murine Chemokine (C-C Motif) Ligand 8
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Involved Pathway

CCL8 involved in several pathways and played different roles in them. We selected most pathways CCL8 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
Ccl27a; IL2RB; Il23a; INHBB; NGFR; IL7; TNFSF10; OSM; CRLF2; CCR6
Chemokine signaling pathway
PIK3CB; PIK3R2; ADRBK2; GNG5; PIK3R1; GM2506; MAP2K1; MAPK3; PRKACB; CXCR1

Protein Function

CCL8 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL8 itself. We selected most functions CCL8 had, and list some proteins which have the same functions with CCL8. You can find most of the proteins on our site.
Function
Related Protein
Function CCR chemokine receptor binding
Related Protein CCL34B.4; CCRL2; CCL20A.3; CCL3L1; CCL16; CXCL32B.1; CCL14; CCL17; CCL3L3; CCL19A.1
Function chemokine activity
Related Protein CXCL18B; CXCL11.8; CCL35.1; CXCL6; CCL5; CCL20A.3; CXCL16; CXL34B.11; CCL22; CCL26
Function heparin binding
Related Protein RSPO3; SERPINE2; THBS2; FBLN7; LIPC; RSPO4; UBE4A; COL13A1; LRPAP1; CTGF
Function phospholipase activator activity
Related Protein CCL5; GM2A; CCL8; PDPK1; APOC2; CCL3; ARHGAP6
Function protein kinase activity
Related Protein CAD; NAT1; NTRK3A; Fert2; CASKB; MAP2K4A; CAMK2G1; RIPK4; PTK2AA; PKDCCA

CCL8 Related Articles

Hayes, LN; Severance, EG; et al. Inflammatory Molecular Signature Associated With Infectious Agents in Psychosis. SCHIZOPHRENIA BULLETIN 40:963-972(2014).
Ludlow, LE; Hasang, W; et al. Peripheral Blood Mononuclear Cells Derived from Grand Multigravidae Display a Distinct Cytokine Profile in Response to P. falciparum Infected Erythrocytes. PLOS ONE 9:-(2014).

CCL8 Related Gene Family

Chemokines Cytokines