CHIT1 Protein, chitinase 1 (chitotriosidase)


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Official Full Name chitinase 1 (chitotriosidase)
Background Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
Synonyms CHIT1; chitinase 1 (chitotriosidase); chitotriosidase-1; CHI3; CHIT; CHIT1_HUMAN; Chitinase 1; Chitinase-1; Chitotriosidase; EC; FLJ00314; MGC125322; Plasma methylumbelliferyl tetra N acetylchitotetraoside hydrolase; OTTHUMP00000039092; OTTHUMP00000217083; OTTHUMP00000217084; OTTHUMP00000217085; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase; CHITD
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • NS0
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CHIT1-11177H Recombinant Human CHIT1, GST-tagged E.coli GST
    Human CHIT1-1238H Recombinant Human CHIT1 Protein, GST-Tagged Wheat Germ GST
    Human CHIT1-1672H Recombinant Human CHIT1 protein, His & T7-tagged E.coli His/T7
    Human CHIT1-2533HCL Recombinant Human CHIT1 cell lysate Human Cell N/A
    Human CHIT1-27067TH Recombinant Human CHIT1 Wheat Germ N/A
    Human CHIT1-3212H Recombinant Human CHIT1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CHIT1-535H Recombinant Human CHIT1 Protein, His-tagged NS0 His
    Human CHIT1-658H Recombinant Human CHIT1, His tagged Human Cell His
    Mouse Chit1-1673M Recombinant Mouse Chit1 protein, His & T7-tagged E.coli His/T7

    CHIT1 involved in several pathways and played different roles in them. We selected most pathways CHIT1 participated on our site, such as Amino sugar and nucleotide sugar metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHIT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Amino sugar and nucleotide sugar metabolism CHIT1; CYB5R4; FPGT; UXS1; UAP1; CMAS; GKUP; GALK1; PGM1; UGP2A

    CHIT1 has several biochemical functions, for example, chitin binding, chitinase activity, endochitinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHIT1 itself. We selected most functions CHIT1 had, and list some proteins which have the same functions with CHIT1. You can find most of the proteins on our site.

    Function Related Protein
    chitin binding FIBCD1; Chil3; CHIA.1; CHI3L1; CTBS; OVGP1; CHIT1; CHIA.2; CHI3L2; CHIA.4
    chitinase activity CHIA.2; CHIA; CHIA.4; OVGP1; CHIA.1; CHIT1; CHID1; CTBS; CHIA.3
    endochitinase activity CHIT1

    CHIT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHIT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHIT1.

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