chit1
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  • Official Full Name
  • chitinase 1 (chitotriosidase)
  • Background
  • Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
  • Synonyms
  • CHIT1; chitinase 1 (chitotriosidase); chitotriosidase-1; CHI3; CHIT; CHIT1_HUMAN; Chitinase 1; Chitinase-1; Chitotriosidase; EC 3.2.1.14; FLJ00314; MGC125322; Plasma methylumbelliferyl tetra N acetylchitotetraoside hydrolase; OTTHUMP00000039092; OTTHUMP00000217083; OTTHUMP00000217084; OTTHUMP00000217085; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase; CHITD
Cat.#:CHIT1-1238HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CHIT1 Protein, GST-Tagged
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Cat.#:CHIT1-3212HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CHIT1 Protein, MYC/DDK-tagged
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Cat.#:CHIT1-11177HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CHIT1, GST-tagged
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Cat.#:CHIT1-1672HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CHIT1 protein, His & T7-tagged
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Cat.#:CHIT1-27067THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CHIT1
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Cat.#:CHIT1-27068THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CHIT1
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Cat.#:CHIT1-535HTag:His
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human CHIT1 Protein, His-tagged
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Cat.#:CHIT1-658HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CHIT1, His tagged
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Cat.#:Chit1-1673MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Chit1 protein, His & T7-tagged
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Cat.#:CHIT1-2533HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CHIT1 cell lysate
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Involved Pathway

CHIT1 involved in several pathways and played different roles in them. We selected most pathways CHIT1 participated on our site, such as Amino sugar and nucleotide sugar metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHIT1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Amino sugar and nucleotide sugar metabolism
GMPPAB; GNE; MPI; FUK; NPL; GMDS; UGP2; UXS1; nanA; GPIB

Protein Function

CHIT1 has several biochemical functions, for example, chitin binding, chitinase activity, endochitinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHIT1 itself. We selected most functions CHIT1 had, and list some proteins which have the same functions with CHIT1. You can find most of the proteins on our site.
Function
Related Protein
Function chitin binding
Related Protein OVGP1; CTBS; Chil3; CHIA.2; CHIA; CHIA.3; CHID1; CHIA.1; CHIA.4; FIBCD1
Function chitinase activity
Related Protein CHIA.3; CHIA.2; CHIA.4; CHIT1; CTBS; CHIA; CHID1; CHIA.1; OVGP1
Function endochitinase activity
Related Protein CHIT1