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CLEC2D

  • Official Full Name

    C-type lectin domain family 2, member D

  • Overview

    This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Oct 2010]
  • Synonyms

    CLEC2D; C-type lectin domain family 2, member D; CLAX; LLT1; OCIL; C-type lectin domain family 2 member D; LLT-1; C-type lectin related f; lectin-like transcript 1; lectin-like NK cell receptor; osteoclast inhibitory lectin; C-type lectin superfamily 2, member D;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • hFc
  • Avi
  • His
  • His (Fc)
  • mFc
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CLEC2D-7238H Recombinant Human CLEC2D, His-tagged E.coli His 60-191aa
Human CLEC2D-1464H Recombinant Human CLEC2D Protein, GST-tagged Wheat Germ GST
Human CLEC2D-329H Recombinant Human CLEC2D protein, hFc-Avi-tagged HEK293 hFc-Avi Arg60-Val191
Human CLEC2D-6077H Recombinant Human CLEC2D Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CLEC2D-3236H Recombinant Human CLEC2D Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CLEC2D-327H Recombinant Human CLEC2D protein, mFc-tagged HEK293 mFc Arg 60 - Val 191
Human CLEC2D-614H Recombinant Human CLEC2D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CLEC2D-2133HF Recombinant Full Length Human CLEC2D Protein, GST-tagged In Vitro Cell Free System GST 154 amino acids
Human CLEC2D-329HB Recombinant Human CLEC2D protein, hFc-Avi-tagged, Biotinylated HEK293 hFc-Avi Arg60-Val191
Human CLEC2D-612HFL Recombinant Full Length Human CLEC2D Protein, C-Flag-tagged Mammalian cells Flag
Human CLEC2D-614H-B Recombinant Human CLEC2D Protein Pre-coupled Magnetic Beads HEK293
Mouse CLEC2D-328M Recombinant Mouse CLEC2D protein, His-tagged HEK293 His Leu63-Ser207
Rat Clec2d-547R Recombinant Rat Clec2d protein(Lys98-Leu233), hFc-tagged HEK293 N-hFc Lys98-Leu233
Rat CLEC2D-1438R Recombinant Rat CLEC2D Protein Mammalian Cell His
Rat CLEC2D-737RCL Recombinant Rat CLEC2D cell lysate Human Cell N/A
Rat CLEC2D-1096R Recombinant Rat CLEC2D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CLEC2D-1096R-B Recombinant Rat CLEC2D Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CLEC2D Related Research Area

CLEC2D involved in several pathways and played different roles in them. We selected most pathways CLEC2D participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLEC2D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemCLTA;DNM2;STUB1;CTSS;UBE2U;RNF111;DYNC1I2;CMTM2A;MKRN1
Immune SystemSH3RF1;KLRF1;RAPGEF3;IFIT8;MGC174155;ASB17;KLHL20;ABI1B;FCGR1B
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellCD200R4;CD300LG;LILRA1;LAIR2;GM11711;LILRB4;OSCAR;CD300LF;SIGLEC9

CLEC2D has several biochemical functions, for example, carbohydrate binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLEC2D itself. We selected most functions CLEC2D had, and list some proteins which have the same functions with CLEC2D. You can find most of the proteins on our site.

Function Related Protein
carbohydrate bindingEMC7;LGALS3;CLEC6A;ZP3;GALNTL4;POC1BL;CD209C;ILLR4;CLEC5A
transmembrane signaling receptor activitySEMA4D;CD79A;IL11RA;EGFR;LYVE1;GPR182;CD3G;CLEC4A;GIPR

CLEC2D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLEC2D here. Most of them are supplied by our site. Hope this information will be useful for your research of CLEC2D.

  • Q&As
  • Reviews

Q&As (5)

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How does HLA-DMA contribute to the development of vaccines? 01/13/2023

HLA-DMA's role in antigen presentation is relevant to vaccine development, as it impacts the immune response generated by vaccines and influences the effectiveness of vaccination strategies.

In transplantation, how does HLA-DMA impact graft acceptance or rejection? 05/18/2021

Understanding HLA-DMA's role is crucial in transplantation, as it affects the presentation of antigens from the graft, influencing the immune response and the likelihood of graft acceptance or rejection.

How does HLA-DMA contribute to the adaptive immune response? 06/21/2019

HLA-DMA facilitates the loading of antigenic peptides onto MHC class II molecules, a process essential for the activation of CD4+ T cells and the adaptive immune response.

How does HLA-DMA relate to autoimmune diseases? 11/26/2018

Aberrant antigen presentation mediated by HLA-DMA has been implicated in autoimmune diseases, as it may lead to the presentation of self-antigens and the activation of autoreactive T cells.

Can HLA-DMA be used as a biomarker in disease diagnosis? 05/27/2017

Abnormalities in HLA-DMA expression or function may serve as biomarkers in disease diagnosis, providing insights into the dysregulation of antigen presentation pathways.

Customer Reviews (3)

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Reviews
06/24/2021

    Their commitment to delivering exceptional products and assisting with any challenges that may arise ensures a successful and rewarding experimental journey.

    08/29/2020

      This flexibility enables researchers like myself to tailor CLEC2D protein experiments to our unique needs, enhancing the reliability and relevance of the obtained results.

      11/08/2018

        The CLEC2D protein offered by the manufacturer is of exceptional quality, and it meets the rigorous standards necessary for my experimental needs.

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