clic1
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  • Official Full Name
  • chloride intracellular channel 1
  • Background
  • Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
  • Synonyms
  • CLIC1; chloride intracellular channel 1; chloride intracellular channel protein 1; NCC27; p64CLCP; hRNCC; RNCC protein; chloride channel ABP; nuclear chloride ion channel 27; nuclear chloride ion channel protein; regulatory nuclear chloride ion channel pr
Cat.#:CLIC1-1477HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CLIC1 Protein, GST-tagged
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Cat.#:CLIC1-620HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CLIC1 Protein, His-tagged
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Cat.#:CLIC1-11324HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CLIC1, GST-tagged
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Cat.#:CLIC1-2498HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Chloride Intracellular Channel 1, His-tagged
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Cat.#:CLIC1-262HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CLIC1, His-tagged
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Cat.#:CLIC1-27814THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CLIC1, His-tagged
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Cat.#:CLIC1-27816THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CLIC1, His-tagged
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Cat.#:CLIC1-1448RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CLIC1 Protein
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Cat.#:CLIC1-11958ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CLIC1
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Cat.#:CLIC1-7448HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CLIC1 293 Cell Lysate
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Protein Function

CLIC1 has several biochemical functions, for example, chloride channel activity, NOT glutathione transferase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLIC1 itself. We selected most functions CLIC1 had, and list some proteins which have the same functions with CLIC1. You can find most of the proteins on our site.
Function
Related Protein
Function chloride channel activity
Related Protein GABRE; CLIC5B; TTYH3; CLCNKB; CLCN5; CLCA5; CLCN4; CLICA; SLC26A11; SLC26A2
Function NOT glutathione transferase activity
Related Protein CLIC1; CLIC3; ALOX5AP; CLIC5; CLIC2
Function protein binding
Related Protein LINGO1; KCTD6; CCDC68; PRAC; CTR9; LINC00482; RABAC1; NR5A1; EMP1; TMPRSS15
Function voltage-gated ion channel activity
Related Protein CACNG1A; CACNG8A; CLIC5A; KCNC3A; KCNK16; KCNIP3; CACNA1SB; CACNG2A; KCNG4A; KCNJ16

Interacting Protein

CLIC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLIC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLIC1.
EPB41; MCC; HLA-B; ARF6; IKBKE; LSM1; RPLP1; THRA; ALOX5AP; ATP5F1; ATP6V0C; NTF4; NUP62; MLH1; CPT1A; PRDX4; rpoB; nifJ; hemH1

CLIC1 Related Articles

Averaimo, S; Gritti, M; et al. CLIC1 functional expression is required for cAMP-induced neurite elongation in post-natal mouse retinal ganglion cells. JOURNAL OF NEUROCHEMISTRY 131:444-456(2014).
Setti, M; Savalli, N; et al. Functional Role of CLIC1 Ion Channel in Glioblastoma-Derived Stem/Progenitor Cells. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE 105:1644-1655(2013).