Recombinant Mouse Clic1 Protein, MYC/DDK-tagged

• Cat.No.: Clic1-519M
• Product Overview: Purified recombinant protein of full-length mouse chloride intracellular channel 1 (Clic1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Ubiquitous expression in large intestine adult (RPKM 126.6), thymus adult (RPKM 119.9) and 27 other tissues.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 27 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Clic1 chloride intracellular channel 1 [ Mus musculus (house mouse) ]
• Official Symbol: Clic1
• Synonyms: Clic1; chloride intracellular channel 1; G6; Clcp; chloride intracellular channel protein 1; NCC27; nuclear chloride ion channel 27
• Gene ID: 114584
• mRNA Refseq: NM_033444
• Protein Refseq: NP_254279
• UniProt ID: Q9Z1Q5

Reviews

12/12/2022

With the manufacturer's outstanding technical support, you can be assured that any challenges you encounter will be efficiently addressed.

07/26/2020

Its superior quality, combined with the manufacturer's exceptional technical support, provides researchers with the confidence they need to conduct successful experiments and obtain meaningful results.

11/04/2018

Researchers who have utilized the CLIC1 protein laud its reliability and effectiveness in their studies.

Q&As

How does CLIC1 protein contribute to cancer progression?

CLIC1 protein promotes cancer cell proliferation, migration, and invasion, making it a potential target for cancer therapy.

Are there any clinical trials targeting CLIC1 protein in cancer therapy?

Several clinical trials are investigating the efficacy of CLIC1 protein-targeted therapies in various types of cancer, including breast, lung, and colorectal cancer.

How does CLIC1 protein contribute to cardiovascular disorders?

CLIC1 protein has been linked to cardiac hypertrophy, fibrosis, and arrhythmias, suggesting its involvement in the pathogenesis of cardiovascular diseases.

Can CLIC1 protein be used as a therapeutic target in neurodegenerative diseases?

Yes, targeting CLIC1 protein has shown promise in preclinical studies as a potential therapeutic approach for neurodegenerative diseases.

How is CLIC1 protein involved in neurodegenerative diseases?

CLIC1 protein has been implicated in neurodegenerative diseases such as Alzheimer's and Parkinson's, where it may play a role in neuronal dysfunction and neuroinflammation.