Cd36 Protein, CD36 molecule (thrombospondin receptor)

Cd36

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Cd36

Official Full Name CD36 molecule (thrombospondin receptor)
Background The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]
Synonyms CD36; CD36 molecule (thrombospondin receptor); FAT; GP4; GP3B; GPIV; CHDS7; PASIV; SCARB3; BDPLT10; platelet glycoprotein 4; GPIIIB; PAS IV; PAS-4 protein; glycoprotein IIIb; cluster determinant 36; fatty acid translocase; platelet glycoprotein IV; scavenger receptor class B, member 3; leukocyte differentiation antigen CD36; CD36 antigen (collagen type I receptor, thrombospondin receptor);
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Monkey
    • Mouse
    • Rat
    • Rhesus Macaque
    • Rhesus monkey
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • His
    • GST
    • T7
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Monkey CD36-001M Recombinant Monkey CD36 Protein HEK293
    Rhesus monkey CD36-737R Recombinant Rhesus monkey CD36 Protein, Fc-tagged HEK293 Fc
    Human CD36-0794H Recombinant Human CD36 Protein Wheat Germ N/A
    Human CD36-0795H Recombinant Human CD36 Protein, GST-Tagged Wheat Germ GST
    Human CD36-179H Recombinant Human CD36 protein, His-tagged HEK293 His
    Human CD36-22H Recombinant Human CD36 Protein, Fc-tagged Insect Cell Fc
    Human CD36-2539HCL Recombinant Human CD36 cell lysate Human Cell N/A
    Human CD36-257H Recombinant Human CD36 protein, His-tagged Insect Cell His
    Human CD36-27868TH Recombinant Human CD36, His-tagged Wheat Germ His
    Human CD36-3084H Recombinant Human CD36 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CD36-3184H Recombinant Human CD36, His tagged Human Cell His
    Human CD36-7084H Recombinant Human CD36 protein, His & T7-tagged E.coli His/T7
    Mouse CD36-2400MCL Recombinant Mouse CD36 cell lysate Human Cell N/A
    Mouse Cd36-3322M Recombinant Mouse Cd36, Fc-His tagged Human Cell Fc/His
    Mouse Cd36-3323M Recombinant Mouse Cd36 protein, His-tagged HEK293 His
    Mouse Cd36-365M Recombinant Mouse Cd36 Protein, His-tagged Insect Cell His
    Mouse Cd36-7085M Recombinant Mouse Cd36 protein, His & T7-tagged E.coli His/T7
    Rat CD36-1236RCL Recombinant Rat CD36 cell lysate Human Cell N/A
    Rat Cd36-7086R Recombinant Rat Cd36 protein, His & T7-tagged E.coli His/T7
    Rat Cd36-8751R Recombinant Rat Cd36, Fc tagged Human Cell Fc
    Cynomolgus Monkey CD36-1109CCL Recombinant Cynomolgus CD36 cell lysate Human Cell N/A
    Cynomolgus Monkey CD36-96C Recombinant Cynomolgus CD36, Fc tagged Human Cell N/A
    Rhesus Macaque CD36-736R Recombinant Rhesus monkey CD36 Protein, His-tagged Mammalian Cell His
    Chicken CD36-2432C Recombinant Chicken CD36 Mammalian Cell His
    Zebrafish CD36-508Z Recombinant Zebrafish CD36 Mammalian Cell His

    Cd36 involved in several pathways and played different roles in them. We selected most pathways Cd36 participated on our site, such as PPAR signaling pathway, Phagosome, AMPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cd36 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    PPAR signaling pathway CYP4A12A; RXRG; ME1; CYP7A1A; FABP2; SLC27A1A; ACADL; RXRGA; CD36; CYP27A1
    Phagosome ATP6V1B2; TLR4; BMA2; RAB7; ITGA5; ATP6V1BA; HLA-A; BLB2; HLA-DOA; ITGB2
    AMPK signaling pathway SLC2A4; PFKFB1; STK11; PIK3CG; FBP1; CPT1A; G6PC3; CPT1B; SCD; PPP2R5C
    ECM-receptor interaction ITGB3B; SDC4; GP1BA; ITGA3B; ITGB1B.2; GP5; ITGA5; HSPG2; COL1A1B; COL27A1A
    Hematopoietic cell lineage CD14; THPO; CSF1R; CD24; IL5; ITGA4; Kitl; CD3E; CD3D; FCGR1A; Il4ra
    Adipocytokine signaling pathway JAK2; PRKAG3; NPY; ACSL3A; NFKBIAA; LEPA; TNFRSF1B; MTOR; ACSL4; SLC2A4
    Insulin resistance INS2; ACACB; CREB3L1; PPP1R3B; CD36; PPP2R4; PRKAB1B; MAPK8A; SLC27A1A; SLC27A5
    Fat digestion and absorption APOA4; MOGAT3; PPAP2C; PLA2G2D; DGAT2; PLA2G3; PLA2G12B; ABCA1; PLA2G2A; PLA2G10
    Malaria MYD88; HBB-B2; IL1B; SDC1; VCAM1; CD36; KLRK1; SDC2; ICAM1; THBS2

    Cd36 has several biochemical functions, for example, MAP-kinase scaffold activity, kinesin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Cd36 itself. We selected most functions Cd36 had, and list some proteins which have the same functions with Cd36. You can find most of the proteins on our site.

    Function Related Protein
    MAP-kinase scaffold activity JIP1; SPAG9A; KSR1; MAPK8IP3; MAPK8IP2; DUSP19; CD36; SPAG9
    kinesin binding PLEKHM2; SPAG9; SERPINB1A; DISC1; SNCA; CD36; KLC3; MAPK8IP3; NEFH; SPAG9A
    protein binding DNAJB5; PPP1R9A; COMT; WIPF2; PIKFYVE; MC3R; LYVE1; PCP4; RNMT; TRIP12
    protein kinase binding PTEN; CCND1; XBP1; PAK2; TELO2; CCND2; BORA; BAD; PARK2; HSPB1
    protein kinase inhibitor activity SOCS1; TAOK3; CAMK2N1A; MBIP; DUSP19; SOCS1A; TSACC; JIP1; SOCS1B; PRKRIP1

    Cd36 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cd36 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cd36.

    dacD; cutA; q7ciq1_yerpe; yapE; icc; CHRD; cona_canen

    Puig, KL; Manocha, GD; et al. Amyloid Precursor Protein Mediated Changes in Intestinal Epithelial Phenotype In Vitro. PLOS ONE 10:-(2015).
    He, L; Zhou, XM; et al. Comparative Study of the Growth and Survival of Recombinant Mycobacterium smegmatis Expressing Mce4A and Mce4E from Mycobacterium bovis. DNA AND CELL BIOLOGY 34:125-132(2015).

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