Description : |
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
His |
Form : |
Lyophilized |
Molecular Mass : |
47.5 kDa |
Protein Length : |
472 |
AA Sequence : |
MGCDRNCGLIAGAVIGAVLAVFGGI LMPVGDLLIQKTIKKQVVLEEGTIA FKNWVKTGTEVYRQFWIFDVQNPQE VMMNSSNIQVKQRGPYTYRVRFLAK ENVTQDAEDNTVSFLQPNGAIFEPS LSVGTEADNFTVLNLAVAAASHIYQ NQFVQMILNSLINKSKSSMFQVRTL RELLWGYRDPFLSLVPYPVTTTVGL FYPYNNTADGVYKVFNGKDNISKVA IIDTYKGKRNLSYWESHCDMINGTD AASFPPFVEKSQVLQFFSSDICRSI YAVFESDVNLKGIPVYRFVLPSKAF ASPVENPDNYCFCTEKIISKNCTSY GVLDISKCKEGRPVYISLPHFLYAS PDVSEPIDGLNPNEEEHRTYLDIEP ITGFTLQFAKRLQVNLLVKPSEKIQ VLKNLKRNYIVPILWLNETGTIGDE KANMFRSQVTGKINLLGLIEMILLS VGVVMFVAFMISYCACRSKTIK |
Purity : |
> 98% |
Applications : |
WB; ELISA; FACS; FC |
Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
Storage : |
At -20 centigrade. |
Concentration : |
1 mg/mL |
Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |