Recombinant Full Length Human CD36 molecule (thrombospondin receptor) VLPs, GFP-tagged

Cat.No. : CD36-001HV
Product Overview : Recombinant Full Length Human CD36 VLPs with GFP-tag was expressed in HEK293.
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Description : The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene.
Source : HEK293
Species : Human
Tag : C-EGFP
Protein length : Full length
AA Sequence : GCDRNCGLIAGAVIGAVLAVFGGIL MPVGDLLIQKTIKKQVVLEEGTIAF KNWVKTGTEVYRQFWIFDVQNPQEV MMNSSNIQVKQRGPYTYRVRFLAKE NVTQDAEDNTVSFLQPNGAIFEPSL SVGTEADNFTVLNLAVAAASHIYQN QFVQMILNSLINKSKSSMFQVRTLR ELLWGYRDPFLSLVPYPVTTTVGLF YPYNNTADGVYKVFNGKDNISKVAI IDTYKGKRNLSYWESHCDMINGTDA ASFPPFVEKSQVLQFFSSDICRSIY AVFESDVNLKGIPVYRFVLPSKAFA SPVENPDNYCFCTEKIISKNCTSYG VLDISKCKEGRPVYISLPHFLYASP DVSEPIDGLNPNEEEHRTYLDIEPI TGFTLQFAKRLQVNLLVKPSEKIQV LKNLKRNYIVPILWLNETGTIGDEK ANMFRSQVTGKINLLGLIEMILLSV GVVMFVAFMISYCACRSKTIK
Endotoxin : < 1 EU/μg by LAL.
Notes : Mix the sample gently by repeatedly pipetting it up and down. Do not vortex. Repeated freezing and thawing is not recommended.
The immunization strategy should be optimized (antigen dose, regimen and adjuvant).
Storage : Store it under sterile conditions at -20 to -80 centigrade twelve months from the date of receipt.
Storage Buffer : Lyophilized from a 0.2 μm sterile filtered PBS, 6 % Trehalose, pH 7.4. The volume before lyophilization is 82μl/vial.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot for long-term storage at -80 centigrade.
Solubilize for 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vertexing.
Gene Name : CD36 CD36 molecule (thrombospondin receptor) [Homo sapiens (human)]
Official Symbol : CD36
Synonyms : CD36; CD36 molecule (thrombospondin receptor); CD36 antigen (collagen type I receptor, thrombospondin receptor); platelet glycoprotein 4; FAT; GP3B; GP4; GPIV; SCARB3; GPIIIB; PAS IV; PAS-4 protein; glycoprotein IIIb; cluster determinant 36; fatty acid translocase; platelet glycoprotein IV; scavenger receptor class B, member 3; leukocyte differentiation antigen CD36; CHDS7; PASIV; BDPLT10
Gene ID : 948
mRNA Refseq : NM_000072
Protein Refseq : NP_000063
MIM : 173510
UniProt ID : P16671

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (3)

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Reviews
05/21/2020

    Dependable protein purification, consistently high-quality results.

    04/10/2019

      Great antibody validation, enhances our immunoprecipitation experiments.

      12/28/2018

        Swift protein expression optimization, invaluable for our research efficiency.

        Q&As (7)

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        What is the impact of CD36 on inflammation and the immune response, particularly in chronic inflammatory diseases? 01/23/2022

        CD36 is involved in inflammation and immune responses, potentially exacerbating chronic inflammatory conditions.

        How do alterations in CD36 expression or activity affect obesity and related health complications? 07/08/2021

        Variations in CD36 function can influence the risk of obesity and associated health issues like metabolic syndrome.

        What are the mechanisms by which CD36 modulates cell signaling and energy homeostasis? 03/15/2021

        CD36 modulates cell signaling related to energy utilization and storage, impacting metabolic health.

        How does CD36 contribute to the pathogenesis of metabolic disorders, such as insulin resistance and type 2 diabetes? 03/01/2021

        CD36 affects the development of metabolic disorders by influencing lipid metabolism and insulin sensitivity.

        How does CD36 influence taste perception, especially in the detection of dietary fats? 06/27/2020

        CD36 aids in taste perception, particularly in detecting and responding to dietary fats.

        What role does CD36 play in the development of cardiovascular diseases like atherosclerosis? 02/09/2020

        CD36 is implicated in cardiovascular diseases, contributing to the formation of atherosclerotic plaques.

        How does CD36 (Cluster of Differentiation 36) function in fatty acid metabolism and uptake? 08/27/2019

        CD36 facilitates the uptake and metabolism of fatty acids in cells, playing a critical role in lipid processing.

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