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EIF4E2

  • Official Full Name

    eukaryotic translation initiation factor 4E family member 2

  • Overview

    Eukaryotic initiation factor 4E (eIF4E) binds to the mRNA cap structure to mediate the initiation of translation (1,2). eIF4E interacts with eIF4G, a scaffold protein that promotes assembly of eIF4E and eIF4A into the eIF4F complex (2). eIF4B is thought t
  • Synonyms

    EIF4E2; eukaryotic translation initiation factor 4E family member 2; EIF4EL3, eukaryotic translation initiation factor 4E like 3; eukaryotic translation initiation factor 4E type 2; 4EHP; IF4e; eIF4E type 2; eIF-4E type 2; eIF4E-like protein 4E-LP; mRNA;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EIF4E2-12379H Recombinant Human EIF4E2, GST-tagged E.coli GST 1-245a.a.
Human EIF4E2-154H Recombinant Human EIF4E2 protein, T7-tagged E.coli T7
Human EIF4E2-28495TH Recombinant Human EIF4E2, T7 -tagged E.coli T7
Human EIF4E2-3200H Recombinant Human EIF4E2 Protein, GST-tagged Wheat Germ GST
Human EIF4E2-6650HCL Recombinant Human EIF4E2 293 Cell Lysate HEK293 N/A
Human EIF4E2-01H Recombinant Human EIF4E2 protein, Myc/DDK-tagged HEK293T Myc/DDK
Human EIF4E2-2160H Recombinant Human EIF4E2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EIF4E2-829H-B Recombinant Human EIF4E2 Protein Pre-coupled Magnetic Beads HEK293
Human EIF4E2-4290HF Recombinant Full Length Human EIF4E2 Protein, GST-tagged In Vitro Cell Free System GST 245 amino acids
Human EIF4E2-829H Recombinant Human EIF4E2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human EIF4E2-2032HFL Recombinant Full Length Human EIF4E2 Protein, C-Flag-tagged Mammalian cells Flag
Mouse Eif4e2-2787M Recombinant Mouse Eif4e2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque EIF4E2-1429R Recombinant Rhesus monkey EIF4E2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque EIF4E2-1253R-B Recombinant Rhesus Macaque EIF4E2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque EIF4E2-1253R Recombinant Rhesus Macaque EIF4E2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish EIF4E2-2285Z Recombinant Zebrafish EIF4E2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

EIF4E2 involved in several pathways and played different roles in them. We selected most pathways EIF4E2 participated on our site, such as RNA transport, HIF- signaling pathway, mTOR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF4E2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA transportEIF3EA;NUP62;EIF2S2;ALYREF;EIF1B;XPOT;EIF4A1B;EIF3B;SRRM1
HIF- signaling pathwayHKDC1;Trf;ENO2;NFKB1;HK2;ENO1;SLC2A1;AKT2;RPS6KB1
mTOR signaling pathwayPRKCA;TSC2;PIK3R3B;RRAGCB;PIK3CD;MAPK1;PIK3R5;RRN3;RPS6KA3B
PIK-Akt signaling pathwayFGFR2;INSR;GNB2;IL2RA;ITGA9;IKBKB;TNC;GHR;KIT
Insulin signaling pathwayPPP1R3C;ARAF;EXOC7;SOCS1;EIF4E1C;NRAS;PRKAB1B;SOCS2;PRKACBA

EIF4E2 has several biochemical functions, for example, RNA cap binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF4E2 itself. We selected most functions EIF4E2 had, and list some proteins which have the same functions with EIF4E2. You can find most of the proteins on our site.

Function Related Protein
RNA cap bindingEIF4E;LARP1;EIF4E2;EIF4A1;EIF4G3;NCBP1;NCBP2;SNUPN
poly(A) RNA bindingSRFBP1;NSUN5;PES1;DHX9;RPL11;ARCN1;PPIG;NOL11;NSBP1
protein bindingMYOZ2;MAGI2;ASCC1;BSX;FKBP1A;NR4A1;PIK3C3;CC2D2A;SLC52A2
translation factor activity, RNA bindingABCF1;EEF1A2;EIF2S3;EIF4H;MTIF3;GTF2H3;CPEB4;CPEB2;PPP1R2P9
translation initiation factor activityDENR;MTIF2;MTIF3;EIF4A1B;EIF3EA;EIF3HA;EIF3BA;GTPBP1L;EIF4H
ubiquitin protein ligase bindingTNFRSF14;FAF1;SQSTM1;CCDC50;CKB;KCNQ3;PIAS1;UBE2G1;ERBB2

EIF4E2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF4E2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF4E2.

EIF4ENIF1; KRT13; NECAB2; SPRY2; TADA2A; KRT19; TRIM27

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