eif4e2
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  • Official Full Name
  • eukaryotic translation initiation factor 4E family member 2
  • Background
  • Eukaryotic initiation factor 4E (eIF4E) binds to the mRNA cap structure to mediate the initiation of translation (1,2). eIF4E interacts with eIF4G, a scaffold protein that promotes assembly of eIF4E and eIF4A into the eIF4F complex (2). eIF4B is thought t
  • Synonyms
  • EIF4E2; eukaryotic translation initiation factor 4E family member 2; EIF4EL3, eukaryotic translation initiation factor 4E like 3; eukaryotic translation initiation factor 4E type 2; 4EHP; IF4e; eIF4E type 2; eIF-4E type 2; eIF4E-like protein 4E-LP; mRNA
Cat.#:EIF4E2-3200HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EIF4E2 Protein, GST-tagged
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Cat.#:EIF4E2-12379HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EIF4E2, GST-tagged
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Cat.#:EIF4E2-154HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EIF4E2 protein, T7-tagged
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Cat.#:EIF4E2-28495THTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EIF4E2, T7 -tagged
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Cat.#:EIF4E2-1429RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey EIF4E2 Protein, His-tagged
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Cat.#:EIF4E2-2285ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish EIF4E2
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Cat.#:EIF4E2-6650HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human EIF4E2 293 Cell Lysate
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Involved Pathway

EIF4E2 involved in several pathways and played different roles in them. We selected most pathways EIF4E2 participated on our site, such as RNA transport, HIF- signaling pathway, mTOR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF4E2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
RNA transport
POP5; EIF3A; EIF2S3Y; SMN; EIF4G2; ALYREF; EIF5B; TPRB; RBM8A; EIF4E2
HIF- signaling pathway
RPS6KB1; IGF1R; PIK3R3; HK3; INSR; CAMK2D; GM5506; NFKB1; NOX1; PLCG1
mTOR signaling pathway
RPTOR; PIK3CA; DDIT4; POLDIP3; PRKCA; PTENB; EIF4BA; PIK3R3B; PRKCB; STK11
PIK-Akt signaling pathway
BCL2L1; LPAR6; RHEB; CCND1; IFNA17; COL6A5; FGF21; PDGFA; PKN1; GYS2
Insulin signaling pathway
PYGL; SHC4; RAF1; PIK3CA; EIF4E1B; GRB2A; MAP2K2A; FBP1A; HRAS; IRS4

Protein Function

EIF4E2 has several biochemical functions, for example, RNA cap binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF4E2 itself. We selected most functions EIF4E2 had, and list some proteins which have the same functions with EIF4E2. You can find most of the proteins on our site.
Function
Related Protein
Function RNA cap binding
Related Protein EIF4A1; NCBP2; EIF4E; EIF4E2; SNUPN; EIF4G3; NCBP1; LARP1
Function poly(A) RNA binding
Related Protein RPS6; EIF4A3; MKRN2; EEF2; CDC5L; RPN1; CCDC9; SPTBN1; RPS15A; RPS3A
Function protein binding
Related Protein ARMCX5; RPL10; KRT17; PDZD11; ZNF785; MEN1; MTMR7; ZC3HC1; CDCP1; TRAM1
Function translation factor activity, RNA binding
Related Protein ABCF1; EIF5; EEF1D; EIF4E2; EEF2K; CPEB1; CPEB3; EIF4G2; EIF2S3; SOX11
Function translation initiation factor activity
Related Protein EIF3EB; EIF4E1C; EIF4EA; EIF1AD; EIF2S1B; BRF1A; EIF4E; EIF4E1B; MCTS1; EIF1AXA
Function ubiquitin protein ligase binding
Related Protein UBE2S; TRP53; SKI; WASH; NFKBIA; SMAD2; PIAS1; HSPA9; FANCL; USP25

Interacting Protein

EIF4E2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF4E2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF4E2.
EIF4ENIF1; KRT13; NECAB2; SPRY2; TADA2A; KRT19; TRIM27