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Official Full Name eukaryotic translation initiation factor 4E family member 2
Background Eukaryotic initiation factor 4E (eIF4E) binds to the mRNA cap structure to mediate the initiation of translation (1,2). eIF4E interacts with eIF4G, a scaffold protein that promotes assembly of eIF4E and eIF4A into the eIF4F complex (2). eIF4B is thought t
Synonyms EIF4E2; eukaryotic translation initiation factor 4E family member 2; EIF4EL3, eukaryotic translation initiation factor 4E like 3; eukaryotic translation initiation factor 4E type 2; 4EHP; IF4e; eIF4E type 2; eIF-4E type 2; eIF4E-like protein 4E-LP; mRNA
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EIF4E2-2160H Recombinant Human EIF4E2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Eif4e2-2787M Recombinant Mouse Eif4e2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human EIF4E2-12379H Recombinant Human EIF4E2, GST-tagged E.coli GST
    Human EIF4E2-154H Recombinant Human EIF4E2 protein, T7-tagged E.coli T7
    Human EIF4E2-28495TH Recombinant Human EIF4E2, T7 -tagged E.coli T7
    Human EIF4E2-3200H Recombinant Human EIF4E2 Protein, GST-tagged Wheat Germ GST
    Human EIF4E2-6650HCL Recombinant Human EIF4E2 293 Cell Lysate HEK293 N/A
    Rhesus Macaque EIF4E2-1429R Recombinant Rhesus monkey EIF4E2 Protein, His-tagged Mammalian Cell His
    Zebrafish EIF4E2-2285Z Recombinant Zebrafish EIF4E2 Mammalian Cell His

    EIF4E2 involved in several pathways and played different roles in them. We selected most pathways EIF4E2 participated on our site, such as RNA transport, HIF- signaling pathway, mTOR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF4E2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA transport EIF2S3Y; DDX39B; NUP88; RANBP2; SMN2; SUMO3A; EIF3B; POP1; EIF3BA; EIF4G3
    HIF- signaling pathway ENO2; VEGFA; CAMK2A; ANGPT1; GM5506; PIK3CG; INS2; MTOR; ERBB2; PRKCB
    mTOR signaling pathway INSB; RPS6KA3B; PDPK1; RRAGD; ULK2; IKBKB; TSC1A; PRKAA1; PIK3R5; EIF4E2
    PIK-Akt signaling pathway SOS1; INSR; GNB3; INS1; PPP2CA; HGF; ITGA9; GNG7; IBSP; PIK3CA
    Insulin signaling pathway SLC2A4; RHOQ; AKT1; PIK3R3B; PRKAR1AB; PIK3CB; RAPGEF1; G6PC3; GYS1; PHKA2

    EIF4E2 has several biochemical functions, for example, RNA cap binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF4E2 itself. We selected most functions EIF4E2 had, and list some proteins which have the same functions with EIF4E2. You can find most of the proteins on our site.

    Function Related Protein
    RNA cap binding NCBP2; EIF4G3; EIF4E; LARP1; NCBP1; SNUPN; EIF4A1; EIF4E2
    poly(A) RNA binding ALDOA; SUMO1; CCDC55; ADAR; DHX36; SRFBP1; DCAF13; SRP19; RBM26; CDK13
    protein binding ZNF83; SLC35F6; ALKBH8; EP300; TEX264; FYB; SIRT1; FAM193B; PVRL2; KBTBD6
    translation factor activity, RNA binding CPEB1A; GTF2H2; EIF5; EEF2K; EIF4G3; EIF4H; CPEB1B; ABCF1; CPEB2; CPEB4
    translation initiation factor activity EIF1AY; EIF3S10; EIF6; EIF3J; MTIF2; AGO2; EIF2S1; DENR; EIF2D; EIF3HB
    ubiquitin protein ligase binding WASH1; UCHL1; MOAP1; CXCR4; SPG20; CUL1B; GPI; HERC2; UBXN1; ABI2

    EIF4E2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF4E2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF4E2.


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