Recombinant Human EIF4E2 protein, Myc/DDK-tagged

• Cat.No.: EIF4E2-01H
• Product Overview: Recombinant Human EIF4E2 protein, fused to Myc/DDK-tag, was expressed in HEK293T. Protein Families: Transcription Factors. Protein Pathways: Insulin signaling pathway, mTOR signaling pathway.

Specification

• Description: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation. Acts as a repressor of translation initiation. In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap (By similarity).
• Source: HEK293T
• Species: Human
• Tag: Myc/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 28.2 kDa
• Product-Related Proteins: TA50011-100
  LC401518
  RC201391
  
  LC401518
  TA502403
  RC201391
• Purity: > 80%
• Usage: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL

Gene Information

• Gene Name: EIF4E2 eukaryotic translation initiation factor 4E family member 2 [ Homo sapiens (human) ]
• Official Symbol: EIF4E2
• Synonyms: 4E-LP; 4EHP; EIF4EL3; h4EHP; IF4e
• Gene ID: 9470
• mRNA Refseq: NM_004846.4
• Protein Refseq: NP_004837.1
• MIM: 605895
• UniProt ID: O60573