Recombinant Full Length Human EIF4E2 Protein, C-Flag-tagged

• Cat.No.: EIF4E2-2032HFL
• Product Overview: Recombinant Full Length Human EIF4E2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Enables ubiquitin protein ligase binding activity. Involved in positive regulation of miRNA mediated inhibition of translation. Acts upstream of or within negative regulation of translation. Located in P-body. Part of mRNA cap binding activity complex.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 28.2 kDa
• AA Sequence: MNNKFDALKDDDSGDHDQNEENSTQ KDGEKEKTERDKNQSSSKRKAVVPG PAEHPLQYNYTFWYSRRTPG RPTSSQSYEQNIKQIGTFASVEQFW RFYSHMVRPGDLTGHSDFHLFKEGI KPMWEDDANKNGGKWIIRLR KGLASRCWENLILAMLGEQFMVGEE ICGAVVSVRFQEDIISIWNKTASDQ ATTARIRDTLRRVLNLPPNT IMEYKTHTDSIKMPGRLGPQRLLFQ NLWKPRLNVP TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transcription Factors
• Protein Pathways: Insulin signaling pathway, mTOR signaling pathway

Gene Information

• Gene Name: EIF4E2 eukaryotic translation initiation factor 4E family member 2 [ Homo sapiens (human) ]
• Official Symbol: EIF4E2
• Synonyms: 4EHP; IF4e; 4E-LP; h4EHP; EIF4EL3
• Gene ID: 9470
• mRNA Refseq: NM_004846.4
• Protein Refseq: NP_004837.1
• MIM: 605895
• UniProt ID: O60573