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GCG

  • Official Full Name

    glucagon

  • Overview

    The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
  • Synonyms

    GCG; GLP 1; GLP 2; GLP-1; GLP-1(7-36); GLP-1(7-37); GLP-2; GLP2; GLUC_HUMAN; glucagon; Glucagon like peptide 1; Glucagon-like peptide 2; GRPP; <br/>OXM; OXY;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Therapeutic Proteins
  • Protein Pre-coupled Magnetic Beads
  • Transfected Stable Cell Lines
  • Chicken
  • Human
  • Mouse
  • Pig
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Synthetic
  • Wheat Germ
  • Yeast
  • C
  • His
  • GST
  • HIgG4 Fc
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GCG-13191H Recombinant Human GCG, His-tagged E.coli His 1-180a.a.
Human GCG-370H Synthetic Human Glucagon Synthetic N/A
Human GCG-20H Recombinant Human GCG protein, His-tagged HEK293 His
Human GCG-89H Recombinant Human Glucagon (7-36) E.coli N/A
Human GCG-30529TH Recombinant Human GCG E.coli N/A
Human GCG-215H Recombinant Human GCG Mammalian Cell His
Human GCG-5990HCL Recombinant Human GCG 293 Cell Lysate HEK293 N/A
Human GCG-2949H Recombinant Human GCG protein, GST-tagged E.coli GST 53-89aa
Human GLP1&ALB-P020H Recombinant Human GCG/ALB therapeutic protein N/A
Human GCG-P011H Recombinant Human GCG, HIgG4 Fc-tagged therapeutic protein HIgG4 Fc
Human GCG-4793H Recombinant Human GCG Protein, GST-tagged Wheat Germ GST
Human GCG-2950H Recombinant Human GCG protein, His-GST-tagged E.coli His/GST 53-89aa
Human GCG-P043H Recombinant Human GCG therapeutic protein E.coli N/A
Human GCG-1261H Recombinant Human GCG Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human GCG-2196H Recombinant Human GCG Protein, His-tagged E.coli N-His His146-Asp178*2
Human GCG-3023H Recombinant Human GCG Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human GCG-4969H Recombinant Human GCG Protein, His-tagged E.coli His
Human GCG-01H Recombinant Human GCG Protein, His-Tagged E.coli His 90-180 aa
Human GCG-5412H Recombinant Human GCG protein, His-tagged Yeast His 53-89aa
Human GCG-3046H Recombinant Human GCG Protein (Arg21-Lys180), C-His tagged Mammalian cells C-His Arg21-Lys180
Human GCG-1451H Recombinant Human GCG Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GCG-3023H-B Recombinant Human GCG Protein Pre-coupled Magnetic Beads HEK293
Human GCG-5169HF Recombinant Full Length Human GCG Protein, GST-tagged In Vitro Cell Free System GST 180 amino acids
Human GCG-3044H Recombinant Human GCG Protein (Arg21-Lys180), N-His tagged E.coli N-His Arg21-Lys180
Mouse Gcg-6744M Recombinant Mouse Gcg protein, His & T7-tagged E.coli His/T7 His21~Lys180 (Accession # P55095)
Mouse Gcg-3173M Recombinant Mouse Gcg Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat Gcg-6745R Recombinant Rat Gcg protein, His-tagged E.coli His His21~Lys180
Pig GCG-51P Porcine Glucagon Reference standard N/A
Chicken GCG-4104C Recombinant Chicken GCG Mammalian Cell His
GCG-295H Recombinant Human Glucagon Human N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GCG Related Articles
  • GCG Related Research Area

GCG involved in several pathways and played different roles in them. We selected most pathways GCG participated on our site, such as Insulin secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with GCG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Insulin secretionKCNMB1;INS1;GNA11;CREB3L3;PRKACB;ADCYAP1;KCNMA1;SLC2A1;VAMP2

GCG has several biochemical functions, for example, hormone activity, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GCG itself. We selected most functions GCG had, and list some proteins which have the same functions with GCG. You can find most of the proteins on our site.

Function Related Protein
hormone activityCCK;INHBB;PRL2C3;SST;PRL;CCL25;IGF2A;PRL2A1;ADCYAP1B
identical protein bindingPNMA5;DCP1A;EID3;CALHM1;COIL;UBQLN1;PRDX3;ROBO1;DYNLT1A
protein bindingRPS27;MAPK8IP3;DDX23;SPATC1;PARP4;GPS2;DCC;AGRN;ITGB1
receptor bindingFGF18B;GUSB;FKBP1B;SEMA4D;PTK2AA;LAMA2;WNT2BA;DPP4;HTT

GCG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GCG here. Most of them are supplied by our site. Hope this information will be useful for your research of GCG.

DPP4; FAP; INS; TBC1D1

Zhu, YT; Ren, XY; et al. Fast identification of lipase inhibitors in oolong tea by using lipase functionalised Fe3O4 magnetic nanoparticles coupled with UPLC-MS/MS. FOOD CHEMISTRY 173:521-526(2015).
Alisoltani, A; Fallahi, H; et al. RNA-Seq SSRs and small RNA-Seq SSRs: New approaches in cancer biomarker discovery. GENE 560:34-43(2015).
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