gcg
Share
  • Official Full Name
  • glucagon
  • Background
  • The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
  • Synonyms
  • GCG; GLP 1; GLP 2; GLP-1; GLP-1(7-36); GLP-1(7-37); GLP-2; GLP2; GLUC_HUMAN; glucagon; Glucagon like peptide 1; Glucagon-like peptide 2; GRPP;
    OXM; OXY
Cat.#:GCG-1261HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human GCG Protein, MYC/DDK-tagged
+Inquiry
Cat.#:GCG-4793HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GCG Protein, GST-tagged
+Inquiry
Cat.#:GCG-4969HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GCG Protein, His-tagged
+Inquiry
Cat.#:GCG-370HTag:N/A
Source (Host):SyntheticSpecies:Human
Product nameSynthetic Human Glucagon
+Inquiry
Cat.#:GCG-295HTag:N/A
Source (Host):Species:
Product nameRecombinant Human Glucagon
+Inquiry
Cat.#:GCG-13191HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GCG, His-tagged
+Inquiry
Cat.#:GCG-20HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human GCG protein, His-tagged
+Inquiry
Cat.#:GCG-215HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human GCG
+Inquiry
Cat.#:GCG-30529THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GCG
+Inquiry
Cat.#:GCG-89HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Glucagon (7-36)
+Inquiry
Cat.#:Gcg-6744MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Gcg protein, His & T7-tagged
+Inquiry
Cat.#:Gcg-6745RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Gcg protein, His-tagged
+Inquiry
Cat.#:GCG-4104CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GCG
+Inquiry
Cat.#:GCG-5990HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GCG 293 Cell Lysate
+Inquiry
Cat.#:GCG-51PTag:
Source (Host):Species:Pig
Product namePorcine Glucagon Reference standard
+Inquiry
Cat.#:GCG-P011HTag:HIgG4 Fc
Source (Host):Species:Human
Product nameRecombinant Human GCG, HIgG4 Fc-tagged therapeutic protein
+Inquiry
Cat.#:GCG-P043HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GCG therapeutic protein
+Inquiry
Cat.#:GLP1&ALB-P020HTag:
Source (Host):Species:Human
Product nameRecombinant Human GCG/ALB therapeutic protein
+Inquiry
Cat.#:CSC-TP027Tag:
Source (Host):CHOSpecies:Human
Product nameHuman GCG Stable Cell Line-CHO
+Inquiry
Cat.#:CSC-TP069Tag:
Source (Host):E. coliSpecies:Human
Product nameHuman GCG Stable Cell Line-E. coli
+Inquiry

Involved Pathway

GCG involved in several pathways and played different roles in them. We selected most pathways GCG participated on our site, such as Insulin secretion, Glucagon signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GCG were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Insulin secretion
KCNJ11; ITPR3; KCNMB3; CREB5; ATP1B4; GLP1R; CREB3L2; GCG; RYR2; CAMK2D
Glucagon signaling pathway
PHKB; PRKACG; PGAM2; SIRT1; FOXO1; PYGM; GNAS; PPP3CB; PCK1; CREB3L1

Protein Function

GCG has several biochemical functions, for example, glucagon receptor binding, hormone activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GCG itself. We selected most functions GCG had, and list some proteins which have the same functions with GCG. You can find most of the proteins on our site.
Function
Related Protein
Function glucagon receptor binding
Related Protein GCG; GCGB; GCGA
Function hormone activity
Related Protein SST; UCN3L; INHBA; IGF2; SST1.1; PRLH; PRL7B1; INHA; LEP; LHB
Function identical protein binding
Related Protein COL2A1; MTPAP; YWHAZ; CSNK2B; RAD52; CCL3; FAM108A1; BCHE; UAP1; ATXN10
Function protein binding
Related Protein TULP1; GNPDA1; VCPKMT; ERLIN2; KIF21A; BCL2L15; LCAT; STX4A; PSIP1; STRADA
Function receptor binding
Related Protein ICAM3; PVRL2; NSG1; HCK; HNF4A; CX3CL1; DPP4; ECH1; ARRB2; ABL2

Interacting Protein

GCG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GCG here. Most of them are supplied by our site. Hope this information will be useful for your research of GCG.
DPP4; FAP; INS; TBC1D1

GCG Related Articles

Zhu, YT; Ren, XY; et al. Fast identification of lipase inhibitors in oolong tea by using lipase functionalised Fe3O4 magnetic nanoparticles coupled with UPLC-MS/MS. FOOD CHEMISTRY 173:521-526(2015).
Alisoltani, A; Fallahi, H; et al. RNA-Seq SSRs and small RNA-Seq SSRs: New approaches in cancer biomarker discovery. GENE 560:34-43(2015).