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IDO1

  • Official Full Name

    indoleamine 2,3-dioxygenase 1

  • Overview

    Indoleamine 2,3-dioxygenase (IDO) is an enzyme that is responsible for converting tryptophan to kynurenines. IDO is expressed by a wide variety of tissues and IDO can be upregulated by interferon gamma. IDO modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO may be involved in thesuppression of the immune response to tumours and blocking the IDO pathway may be a potential target for immunotherapy.
  • Synonyms

    IDO1; indoleamine 2,3-dioxygenase 1; IDO, INDO, indoleamine pyrrole 2,3 dioxygenase; indole 2,3-dioxygenase; indolamine 2,3 dioxygenase; indoleamine-pyrrole 2,3-dioxygenase; IDO; INDO; IDO-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human cells
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • C
  • Myc
  • DDK
  • DYKDDDDK
  • Flag
  • Gly
  • Pro
  • GST
  • His
  • His (Fc)
  • Avi
  • MYC
  • N/A
  • N
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IDO1-294H Active Recombinant Human IDO1, His-tagged E.coli His
Human IDO1-008H Active Recombinant Human IDO1 protein, His-tagged E.coli His 2-403 (full length)
Human IDO1-3920H Recombinant Human IDO1, His tagged E.coli His
Human IDO1-3829H Recombinant Human IDO1 protein, GST-tagged Insect Cell N/A
Human IDO1-7325H Recombinant Human IDO1, None tagged E.coli N/A
Human IDO1-28269TH Recombinant Human IDO1 Wheat Germ N/A 403 amino acids
Human IDO1-7190H Active Recombinant Human IDO1 protein E.coli N/A Ala2-Gly403
Human IDO1-14054H Recombinant Human IDO1, GST-tagged E.coli GST 1-403a.a.
Human IDO1-5300HCL Recombinant Human IDO1 293 Cell Lysate HEK293 N/A
Human IDO1-085H Recombinant Human IDO1 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human IDO1-1138H-B Recombinant Human IDO1 Protein Pre-coupled Magnetic Beads HEK293
Human IDO1-1138H Recombinant Human IDO1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human IDO1-1419H Recombinant Human IDO1 Protein (1-403 aa), His-tagged Yeast His 1-403 aa
Human IDO1-3920HAF555 Recombinant Human IDO1 Protein, His-tagged, Alexa Fluor 555 conjugated E.coli His 409
Human IDO1-3096H Recombinant Human IDO1 Protein E.coli Tag Free
Human IDO1-3095H Recombinant Human IDO1 Protein (Met1-Gly403), N-His tagged E.coli N-His Met1-Gly403
Human IDO1-01H Recombinant Human IDO1 Protein, His/Avi-tagged E.coli His/Avi
Human IDO1-7325HAF555 Recombinant Human IDO1 Protein, Gly/Pro-tagged, Alexa Fluor 555 conjugated E.coli Gly/Pro 405
Human IDO1-151H Recombinant Human IDO1 Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human IDO1-3920HAF647 Recombinant Human IDO1 Protein, His-tagged, Alexa Fluor 647 conjugated E.coli His 409
Human IDO1-3920HAF488 Recombinant Human IDO1 Protein, His-tagged, Alexa Fluor 488 conjugated E.coli His 409
Human IDO1-7325HAF647 Recombinant Human IDO1 Protein, Gly/Pro-tagged, Alexa Fluor 647 conjugated E.coli Gly/Pro 405
Human IDO1-7325HAF488 Recombinant Human IDO1 Protein, Gly/Pro-tagged, Alexa Fluor 488 conjugated E.coli Gly/Pro 405
Human IDO1-3920HF Recombinant Human IDO1 Protein, His-tagged, FITC conjugated E.coli His 409
Human IDO1-101HFL Active Recombinant Full Length Human IDO1 Protein, C-Flag-tagged Mammalian cells Flag
Human IDO1-7325HF Recombinant Human IDO1 Protein, Gly/Pro-tagged, FITC conjugated E.coli Gly/Pro 405
Human IDO1-254HF Recombinant Full Length Human IDO1 Protein In Vitro Cell Free System 403 amino acids
Human IDO1-2575H Recombinant Human IDO1 protein E.coli N/A Ala2-Gly403
Mouse Ido1-7432M Active Recombinant Mouse Ido1 Protein, His-tagged E.coli His Ala2-Pro407
Mouse Ido1-2126M Recombinant Mouse Indoleamine 2,3-dioxygenase 1, His-tagged E.coli His
Mouse IDO1-7992M Recombinant Mouse IDO1 Protein Mammalian Cell His
Mouse IDO1-2077M Recombinant Mouse IDO1 Protein (1-407 aa), His-tagged Yeast His 1-407 aa
Mouse IDO1-4414M Recombinant Mouse IDO1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse IDO1-4414M-B Recombinant Mouse IDO1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Ido1-6730M Recombinant Mouse Ido1 Protein (Met1-Pro407), N-His tagged E.coli N-His Met1-Pro407
Mouse Ido1-1213M Recombinant Mouse Ido1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat IDO1-2990R Recombinant Rat IDO1 Protein Mammalian Cell His
Rat Ido1-36R Recombinant Rat Ido1 Protein, His-tagged E.coli His
Rat IDO1-2645R Recombinant Rat IDO1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat IDO1-2645R-B Recombinant Rat IDO1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish IDO1-5465Z Recombinant Zebrafish IDO1 Mammalian Cell His
Kit-1755 Human IDO1 Fluorogenic Inhibitor Screening Assay Kit N/A
Kit-1754 Human IDO1 Cell-Based Assay Kit N/A
Kit-1757 Human IDO1 Inhibitor Screening Assay Kit N/A
Kit-1782 Mouse IDO1 Inhibitor Screening Assay Kit N/A
Kit-1758 Human IDO1 Inhibitor Screening Assay Kit (384) N/A
Kit-1756 Human IDO1 Fluorogenic Inhibitor Screening Assay Kit (384) N/A
Kit-2211 Indoleamine 2,3-Dioxygenase 1 Activity Assay Kit N/A
Kit-1763 IDO1 Inhibitor Mechanism of Action Assay Kit N/A
Kit-2388 Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Screening Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IDO1 Related Articles
  • IDO1 Related Research Area

IDO1 involved in several pathways and played different roles in them. We selected most pathways IDO1 participated on our site, such as Tryptophan metabolism, Metabolic pathways, African trypanosomiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with IDO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Tryptophan metabolismIL4I1;OGDH;INMT;HAAO;CAT;ALDH7A1;GCDH;ALDH9A1B;AOX3L1
Metabolic pathwaysCYP4A10;GGT1;IPPK;CBS;MTMR6;B3GNT5A;ALDH5A1;AK7;RABGNT1
African trypanosomiasisAPOL1;HBB;MYD88;PRKCA;HBB-B1;PRKCB;IL1B2;TNF;ICAM1

IDO1 has several biochemical functions, for example, electron carrier activity, heme binding, indoleamine 2,3-dioxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IDO1 itself. We selected most functions IDO1 had, and list some proteins which have the same functions with IDO1. You can find most of the proteins on our site.

Function Related Protein
electron carrier activitySDHB;HAAO;DHRS3;NCF2;COX11;NQO2;DHDH;GLRX2;CYP1A2
heme bindingHRG;HBAE3;CYP2AA6;FAM84B;DUOX2;CYP4A12A;CYGB1;CYP2P8;CYP2C9
indoleamine 2,3-dioxygenase activityIDO1;IDO2
metal ion bindingNRXN3;SDHDA;ZBTB42;RFWD2;ZNF19;ESRRGB;PIR;ZNF395;KLF8
tryptophan 2,3-dioxygenase activityIDO1;IDO2;TDO2;TDO2B;TDO2A

IDO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IDO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IDO1.

q8d0v8_yerpe; PPP1R16A; DDX24; TERF2IP

Theate, I; van Baren, N; et al. Extensive Profiling of the Expression of the Indoleamine 2,3-Dioxygenase 1 Protein in Normal and Tumoral Human Tissues. CANCER IMMUNOLOGY RESEARCH 3:161-172(2015).
Kang, W; Marasco, WA; et al. Anti-tat Hutat2:Fc mediated protection against tat-induced neurotoxicity and HIV-1 replication in human monocyte-derived macrophages. JOURNAL OF NEUROINFLAMMATION 11:-(2014).
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Customer Reviews (3)

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Reviews
08/12/2022

    The product was kept in perfect condition and delivered on time so that I got the perfect product in the shortest time possible.

    05/14/2022

      Customer service contacted me in a timely manner and helped me solve a lot of problems that arose in my experiments.

      03/12/2022

        The purchased proteins helped me to get satisfactory experimental results.

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