Recombinant Human IDO1 Protein, His/Avi-tagged
Cat.No. : | IDO1-01H |
Product Overview : | Human IDO1, also known as Indoleamine 2,3-dioxygenase 1, a.a. 2-403(end) with an N-terminal His-Avi-Tag, was expressed in an E. coli cell expression system. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan. |
Source : | E. coli |
Species : | Human |
Tag : | His/Avi |
Form : | Aqueous buffer solution |
Molecular Mass : | 48 kDa |
Applications : | Useful for studying enzyme kinetics, substrate specificity, and screening inhibitors. |
Stability : | At least 6 months at -80 centigrade |
Storage : | At -80 centigrade |
Concentration : | 1.12 mg/mL |
Storage Buffer : | 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04 % Tween 20, 20 % glycerol |
Gene Name : | IDO1 indoleamine 2,3-dioxygenase 1 [ Homo sapiens (human) ] |
Official Symbol : | IDO1 |
Synonyms : | IDO1; indoleamine 2,3-dioxygenase 1; IDO; INDO; IDO-1; indoleamine 2,3-dioxygenase 1; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine-pyrrole 2,3-dioxygenase; EC 1.13.11.52 |
Gene ID : | 3620 |
mRNA Refseq : | NM_002164 |
Protein Refseq : | NP_002155 |
MIM : | 147435 |
UniProt ID : | P14902 |
Products Types
◆ Recombinant Protein | ||
IDO1-4414M | Recombinant Mouse IDO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
IDO1-085H | Recombinant Human IDO1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
IDO1-1419H | Recombinant Human IDO1 Protein (1-403 aa), His-tagged | +Inquiry |
Ido1-1213M | Recombinant Mouse Ido1 Protein, MYC/DDK-tagged | +Inquiry |
Ido1-2126M | Recombinant Mouse Indoleamine 2,3-dioxygenase 1, His-tagged | +Inquiry |
◆ Lysates | ||
IDO1-5300HCL | Recombinant Human IDO1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1754 | Human IDO1 Cell-Based Assay Kit | +Inquiry |
Kit-1782 | Mouse IDO1 Inhibitor Screening Assay Kit | +Inquiry |
Kit-2211 | Indoleamine 2,3-Dioxygenase 1 Activity Assay Kit | +Inquiry |
Kit-2388 | Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Screening Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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