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IL17D

  • Official Full Name

    interleukin 17D

  • Overview

    The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008]
  • Synonyms

    IL17D; interleukin 17D; IL27; IL-27; IL-17D; interleukin-17D; interleukin 27;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His|GST
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL17D-128H Active Recombinant Human IL17D protein E.coli N/A
Human IL17D-29743TH Recombinant Human IL17D E.coli N/A
Human IL17D-167H Recombinant Human Interleukin 17D E.coli N/A
Human IL17D-7978H Recombinant Human IL17D protein, His & GST-tagged E.coli His/GST Pro35~Cys169 (Accession # Q8TAD2)
Human IL17D-28H Recombinant Human IL17D protein, GST-tagged E.coli GST
Human IL17D-14155H Recombinant Human IL17D, GST-tagged E.coli GST 1-202a.a.
Human IL17D-852HCL Recombinant Human IL17D cell lysate N/A
Human IL17D-5747HF Recombinant Full Length Human IL17D Protein, GST-tagged In Vitro Cell Free System GST 243 amino acids
Human IL17D-3185H Recombinant Human IL17D protein, His-tagged E.coli His 1-202 aa
Human IL17D-129H Recombinant Human IL17D protein E.coli N/A Ala18-Pro202
Human IL17D-5206H Recombinant Human IL17D Protein, GST-tagged Wheat Germ GST
Human IL17D-247H Recombinant Human IL17D Protein (Phe29-Pro243), C-His tagged, Animal-free, Carrier-free E.coli C-His Phe29-Pro243
Human IL17D-3659H Recombinant Human IL17D Protein (Ala18-Pro202), N-His tagged E.coli N-His Ala18-Pro202
Human IL17D-248H Recombinant Human IL17D Protein (Ala18-Pro202), N-His tagged, Animal-free, Carrier-free E.coli N-His Ala18-Pro202
Mouse Il17d-645M Active Recombinant Mouse Interleukin 17D E.coli N/A
Mouse Il17d-01M Active Recombinant Mouse Il17d Protein, His-Tagged E.coli His
Mouse Il17d-111M Recombinant Mouse Il17d Protein (Ala25-Arg205), N-His tagged, Animal-free, Carrier-free E.coli N-His Ala25-Arg205
Mouse Il17d-1664M Recombinant Mouse Il17d Protein, His-tagged E.coli N-His Ala23-Arg205
Rat Il17d-7979R Recombinant Rat Il17d protein, His & T7-tagged E.coli His/T7 Tyr76~Val274
Zebrafish IL17D-2924Z Recombinant Zebrafish IL17D Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IL17D Related Gene Family
  • IL17D Related Research Area

IL17D involved in several pathways and played different roles in them. We selected most pathways IL17D participated on our site, such as Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL17D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Jak-STAT signaling pathwaySOCS3;IFNGR1;IFNA2;IFNPHI1;IL6;PIM1;SOCS2;Il2;IL21R.1

IL17D has several biochemical functions, for example, cytokine activity, cytokine receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL17D itself. We selected most functions IL17D had, and list some proteins which have the same functions with IL17D. You can find most of the proteins on our site.

Function Related Protein
cytokine activityCcl9;CTF1;GM13279;CMTM7;CCL4;Il2;INHBAB;IFNA21;IL5
cytokine receptor bindingIFNA3;IL17C;IFN-a;IL21;IL15L;IL17F;IFNW1;IFNPHI1;IFNA5

IL17D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL17D here. Most of them are supplied by our site. Hope this information will be useful for your research of IL17D.

IL
  • Q&As
  • Reviews

Q&As (10)

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What methodologies are employed to explore the role of IL17D in neuroinflammation and its potential implications in neurological disorders? 05/09/2022

Neuroinflammation models, neuronal cell assays, and CNS analysis explore IL17D's role in neurological contexts.

What techniques are used to characterize the potential pro-tumor or anti-tumor effects of IL17D in cancer development and progression? 11/03/2021

Tumor xenografts, immune cell infiltration analysis, and gene expression profiling dissect IL17D's role in cancer.

How do researchers decipher the distinct roles of IL17D compared to other IL17 family members in immune responses? 03/31/2020

Functional assays, knockout models, and gene expression analyses distinguish IL17D's unique roles.

How is the interaction between IL17D and the gut microbiota investigated, and what are the implications for intestinal homeostasis? 11/24/2019

Microbiota sequencing, gnotobiotic models, and immune cell profiling investigate IL17D-gut microbiota interactions.

How are the effects of IL17D modulation on autoimmune diseases investigated using experimental models and patient samples? 11/12/2019

Animal models, patient samples, and genetic studies elucidate IL17D's involvement in autoimmune diseases.

Can you explain the experimental designs used to study the involvement of IL17D in wound healing and tissue regeneration? 03/17/2018

Wound healing assays, tissue regeneration studies, and histological analyses examine IL17D's effects on tissue repair.

What experimental techniques are employed to investigate the signaling pathways triggered by IL17D and its potential crosstalk with other cytokines? 03/31/2017

Signal transduction assays, phosphoproteomics, and cytokine profiling reveal IL17D's signaling pathways.

What molecular approaches are utilized to assess IL17D's impact on host defense against infections and regulation of mucosal immunity? 03/06/2017

Cell culture models, infection assays, and epithelial barrier assessments uncover IL17D's impact on host defense.

Could you elaborate on the strategies used to study IL17D's contribution to tissue-specific immune cell activation and recruitment? 01/22/2017

Flow cytometry, chemotaxis assays, and adoptive transfer experiments probe IL17D-mediated immune responses.

How are the therapeutic applications of IL17D modulation studied, and what approaches are taken to validate its potential as a therapeutic target? 01/01/2017

Therapeutic antibody testing, RNA interference, and animal disease models validate IL17D as a potential therapy.

Customer Reviews (3)

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Reviews
12/03/2022

    Effective in Th9 differentiation.

    08/14/2019

      Suitable for ELISA.

      08/12/2019

        High bioactivity.

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