il28b
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  • Official Full Name
  • interleukin 28B
  • Background
  • Interleukin-28 (IL-28) is a cytokine that comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses, including the induction of an "antiviral state" by turning on Mx proteins, 2',5'-oligoadenylate synthetase as well as ISGF3G (Interferon Stimulated Gene Factor 3). IL-28A and IL-28B belong to the type III interferon family of cytokines and are highly similar (in amino acid sequence) to IL-29. Their classification as Interferons is due to their ability to induce an antiviral state, while their additional classification as cytokines is due to their chromosomal location as well as the fact that they are encoded by multiple exons, as opposed to a single exon, as most type-I IFNs are.
  • Synonyms
  • Cytokine Zcyto20;IFN lambda 2;IFNL2;IL28A;Interferon lambda 2;Interleukin 28A;ZCYTO20;Il28; IFL-1; IL-28B; INF-alpha; INF-lambda; interleukin-28B; IFN-lambda-3; interleukin 28; interferon alpha; interferon lambda-3; Il28b; interleukin 28B
Cat.#:IL28B-4370ETag:
Source (Host):YeastSpecies:Equine
Product nameRecombinant Equine IL28B Protein
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Cat.#:IL28B-379HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL28B, His tagged
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Cat.#:IL28B-605HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL28B
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Cat.#:IL28B-214MTag:His/Myc
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Interleukin 28B, His-tag, MBP-tag
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Cat.#:IL28B-65MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse IL28B
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Cat.#:IL28B-8163MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse IL28B Protein
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Cat.#:IL28B-600HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Interleukin 28B (interferon, lambda 3)
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Cat.#:Il28b-212MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Interleukin 28B
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Cat.#:Il28b-213MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Interleukin 28B, Carrier Free
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Il28b Related Articles

Oda, K; Uto, H; et al. Impact of a Single Nucleotide Polymorphism Upstream of the IL28B Gene in Patients Positive for Anti-HCV Antibody in an HCV Hyperendemic Area in Japan. JOURNAL OF MEDICAL VIROLOGY 86:1877-1885(2014).
Seaberg, EC; Witt, MD; et al. Differences in hepatitis C virus prevalence and clearance by mode of acquisition among men who have sex with men. JOURNAL OF VIRAL HEPATITIS 21:696-705(2014).

Il28b Related Gene Family

IL