Recombinant Mouse Interleukin 28B, His-tag, MBP-tag
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Cat.No. : | IL28B-214M Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Mouse Interleukin 28B has the matured 174 aa at its C terminal, His tag and MBP tag at the N terminal. It is expressed and purified from an E.coli system. |
Description : | This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). |
Source : | E. coli |
Molecular Mass : | 63.3 kD |
Formulation : | 20 mM Tris-Cl (pH 7.9) 20% Glycerol, 100 mM KCl, 1 mM DTT and 0.2 mM EDTA |
Purity : | >95% based on SDS-PAGE analysis |
Concentration : | 500 µg/ml |
Reconsitution : | Already in liquid form. |
Storage : | -80 °C |
Shipping Conditions : | Dry Ice |
OfficialSymbol : | Il28b |
Gene Name : | Il28b interleukin 28B [ Mus musculus ] |
Synonyms : | Il28b; interleukin 28B; Il28; IFL-1; INF-alpha; IL-28B INF-lambda; interleukin 28; interferon alpha; IFNL3; IL28C; interleukin-28B; IFN-lambda-3; interferon lambda-3 |
Gene ID : | 338374 |
mRNA Refseq : | NM_177396 |
Protein Refseq : | NP_796370 |
UniProt ID : | Q8CGK6 |
Chromosome Location : | 7 A3; 7 |
Pathway : | Jak-STAT signaling pathway |
Function : | cytokine activity; receptor binding |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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