Recombinant Mouse Interleukin 28B

• Cat.No.: Il28b-212M

Specification

• Cat. No.: Il28b-212M
• Description: IL-28A, IL-28B, and IL-29, also named interferon-λ2 (IFN-λ2), IFN-λ3, and IFN-λ1, respectively, are newly identified class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11-13% aa sequence identity) and type I IFN family (15 - 19% aa sequence identity).
• Source: DNA expressed inE.Coli.
• Endotoxin: < 1 EU/µg.
• Reconstitution: It is recommended that sterile PBS containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of no less than 10 μg/mL.
• Buffer: Phosphate-buffered saline (PBS) containing 50µg of BSA per 1µg of cytokine.
• Purity: ≥95%.
• Purification Method: A combination of ion exchange, hydrophobic interaction and size exclusion chromatography.
• Shipping Conditions: Wet ice, Physical State of Product During Shipping is Lyophilized.
• Special Conditions: After receipt, this product should be kept at -70˚C or below for retention of full activity. Upon reconstitution, this cytokine can be stored under sterile conditions at 2˚C to 8˚C for one month or at -20˚C to -70˚C in a manual defrost freezer for three months without detection loss of activity. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: Il28b interleukin 28B [ Mus musculus ]
• Synonyms: Il28b; interleukin 28B; Il28; IFL-1; INF-alpha; INF-lambda; interleukin 28; interferon alpha
• Gene ID: 338374
• mRNA Refseq: NM_177396
• Protein Refseq: NP_796370
• UniProt ID: Q8CGK6
• Chromosome Location: 7 A3
• Pathway: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
• Function: cytokine activity; receptor binding