lgals9
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  • Official Full Name
  • lectin, galactoside-binding, soluble, 9
  • Background
  • The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkins disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.
  • Synonyms
  • LGALS9; lectin, galactoside-binding, soluble, 9; galectin-9; galectin 9; LGALS9A; Ecalectin; Gal-9; galectin9; HOM HD 21; HOM-HD-21; HOMHD21; HUAT; Lectin galactoside binding soluble 9; Lectin galactoside-binding soluble 9; LEG9_HUMAN; LGAL S9; LGALS 9; MGC117375; MGC125973; MGC125974; Tumor antigen HOM-HD-21; Urate transporter/channel protein
Cat.#:LGALS9-2145HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human LGALS9 Protein (1-323 aa), His-tagged
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Cat.#:LGALS9-471HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human LGALS9 Protein, Fc-tagged
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Cat.#:LGALS9-1937HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Lectin, Galactoside-Binding, Soluble, 9, His-tagged
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Cat.#:LGALS9-208HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LGALS9 protein
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Cat.#:LGALS9-432HTag:His|GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LGALS9 Protein, His/GST-tagged
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Cat.#:LGALS9-443HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LGALS9 protein
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Cat.#:LGALS9-445HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human LGALS9 protein, His-tagged
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Cat.#:LGALS9-558HTag:His|GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LGALS9 protein, His & GST-tagged
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Cat.#:LGALS9-7105HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LGALS9, His-tagged
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Cat.#:Lgals9-433MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Lgals9 Protein, His-tagged
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Cat.#:Lgals9-695MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Lgals9
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Cat.#:Lgals9-696MTag:His
Source (Host):Species:Mouse
Product nameRecombinant Mouse Lgals9, His-tagged
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Cat.#:LGALS9-9068MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse LGALS9 Protein
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Cat.#:LGALS9-3392RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat LGALS9 Protein
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Cat.#:Lgals9-435RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Lgals9 Protein, His-tagged
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Cat.#:Lgals9-436RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Lgals9 Protein, His-tagged
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Cat.#:LGALS9-431CTag:His
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle LGALS9 Protein, His-tagged
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Cat.#:LGALS9-4761HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human LGALS9 293 Cell Lysate
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Involved Pathway

LGALS9 involved in several pathways and played different roles in them. We selected most pathways LGALS9 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interleukin-2 signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with LGALS9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine Signaling in Immune system
TNIP2; DUSP1; PEA15A; FGF18B; IFIT2; TRIM29; TRIM38; JAK3; CSF2RA; PELI1
Immune System
POLR3H; POLR3C; C1rb; KIF20A; UBE2J2; POLR3G; SIGLEC10; STUB1; SIGLEC14; GBP1
Interleukin-2 signaling
LGALS9; HAVCR2
Signaling by Interleukins
CASPBL; CASPB; LGALS9; IL1RN; SOCS3A; HAVCR2

Protein Function

LGALS9 has several biochemical functions, for example, carbohydrate binding, disaccharide binding, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LGALS9 itself. We selected most functions LGALS9 had, and list some proteins which have the same functions with LGALS9. You can find most of the proteins on our site.
Function
Related Protein
Function carbohydrate binding
Related Protein GALNT2; CLEC2G; MAN2C1; GALNTL2; MLEC; PVRL1; CD248; ZP3; CLEC4E; GALNT10
Function disaccharide binding
Related Protein LGALS9
Function enzyme binding
Related Protein ARRB2; SNRPD3; HIST1H2AN; TRP53; RYR2; AXIN1; DAXX; CYP2A4; TOP2A; KDM4C
Function galactose binding
Related Protein ENG; CLEC4F; GALK1; LGALS9; COLEC12
Function signal transducer activity
Related Protein OLFR476; CXCR2; ADRB3A; OLFCH1; OLFR494; COPS2; OLFR154; NPFFR1L1; PPM1A; VOPP1

Interacting Protein

LGALS9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LGALS9 here. Most of them are supplied by our site. Hope this information will be useful for your research of LGALS9.
rlmL; q7ard3_yerpe; fhaB4; atoC; q7cji6_yerpe; acoB; malS; q81xz0_bacan; fimD7; syd; cheY; bioD1

LGALS9 Related Articles

Steelman, AJ; Li, JR; et al. Astrocyte galectin-9 potentiates microglial TNF secretion. JOURNAL OF NEUROINFLAMMATION 11:-(2014).
Mizukami, T; Momose, H; et al. System Vaccinology for the Evaluation of Influenza Vaccine Safety by Multiplex Gene Detection of Novel Biomarkers in a Preclinical Study and Batch Release Test. PLOS ONE 9:-(2014).