Recombinant Human LGALS9 protein, His-tagged
Cat.No. : | LGALS9-445H |
Product Overview : | Recombinant Human LGALS9 protein (Ala2-Thr323), fused to His tag at N-terminus, was expressed in human 293 cells (HEK293). |
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Description : | Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 um filtered solution in 20 mM MOPS, 50 mM NaCl, 1 mM EDTA, 2 mM DTT, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 36.6 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE). |
Protein length : | 322 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | LGALS9 |
Official Symbol : | LGALS9 |
Synonyms : | LGALS9; lectin, galactoside-binding, soluble, 9; galectin-9; galectin 9; LGALS9A; gal-9; ecalectin; tumor antigen HOM-HD-21; urate transporter/channel protein; HUAT; MGC117375; MGC125973; MGC125974 |
Gene ID : | 3965 |
mRNA Refseq : | NM_002308 |
Protein Refseq : | NP_002299 |
MIM : | 601879 |
UniProt ID : | O00182 |
Products Types
◆ Recombinant Protein | ||
LGALS9-3048R | Recombinant Rat LGALS9 Protein, His (Fc)-Avi-tagged | +Inquiry |
LGALS9-5058M | Recombinant Mouse LGALS9 Protein, His (Fc)-Avi-tagged | +Inquiry |
LGALS9-660H | Recombinant Human LGALS9 Protein | +Inquiry |
LGALS9-195H | Active Recombinant Human LGALS9 Protein (Ala2-Thr355), N-His tagged, Animal-free, Carrier-free | +Inquiry |
LGALS9-2391D | Recombinant Dog LGALS9 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
LGALS9-4761HCL | Recombinant Human LGALS9 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, there are clinical trials investigating the use of LGALS9-based therapies in cancer treatment, with a focus on immunotherapy approaches.
There is emerging research on the potential use of LGALS9 in modulating immune responses to infectious diseases, particularly in the context of viral infections.
Challenges include optimizing the delivery and dosing of LGALS9-based therapies and addressing potential adverse effects on immune homeostasis.
LGALS9 is being investigated for its potential to induce immune tolerance and mitigate transplant rejection in preclinical studies.
LGALS9 has been found to promote the activation and proliferation of cytotoxic T lymphocytes, which are key players in the immune response against cancer cells.
Customer Reviews (3)
Write a reviewIt has demonstrated outstanding performance in ELISA, providing reliable and precise results.
It has been invaluable in protein electron microscopy structure analysis, facilitating detailed investigations and yielding valuable insights.
I highly recommend the LGALS9 protein for various experimental applications.
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