s100a6
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  • Official Full Name
  • S100 calcium binding protein A6
  • Background
  • Protein S100-A6 is a protein that in humans is encoded by the S100A6 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
  • Synonyms
  • S100A6; 2A9; 5B10; CABP; CACY; PRA; MLN 4; S100 calcium-binding protein A6 (calcyclin); calcyclin; growth factor-inducible protein 2A9; prolactin receptor-associated protein; protein S100-A6
Cat.#:S100A6-228HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human S100A6 Protein, MYC/DDK-tagged
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Cat.#:S100A6-1773HTag:His/S
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human S100A6 protein, His & S-tagged
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Cat.#:S100A6-2212HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human S100A6, His tagged
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Cat.#:S100A6-3101HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human S100A6, None tagged
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Cat.#:S100A6-916HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human S100A6, His-tagged
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Cat.#:S100A6-3100MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse S100A6, None tagged
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Cat.#:S100a6-3552MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse S100a6, His-tagged
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Cat.#:S100a6-845MTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse S100 Calcium Binding Protein A6 (Calcyclin)
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Cat.#:S100a6-1774RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat S100a6 protein, His-tagged
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Cat.#:S100A6-4063RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey S100A6 Protein, His-tagged
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Cat.#:S100A6-1775RTag:His
Source (Host):E. coliSpecies:Rabbit
Product nameRecombinant Rabbit S100A6 protein, His-tagged
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Cat.#:S100A6-5724CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken S100A6
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Cat.#:S100a6-4566MTag:N/A
Source (Host):Species:
Product nameRecombinant Mouse S100 Calcium Binding Protein A6 (Calcyclin)
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Cat.#:S100a6-5106MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse S100 calcium Binding Protein A6 (calcyclin), His-tagged
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Cat.#:S100a6-43MTag:
Source (Host):Species:Mouse
Product nameNative Mouse S100A6
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Cat.#:S100A6-690HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human S100A6 cell lysate
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Involved Pathway

S100A6 involved in several pathways and played different roles in them. We selected most pathways S100A6 participated on our site, such as Gastric cancer network 2, Prostaglandin Synthesis and Regulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with S100A6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Gastric cancer network 2
S100A6; LBR; MTDH; SNURF; DSCC1; TOP2A; BRIX1; PLAC8; SNRPN; RNF144B
Prostaglandin Synthesis and Regulation
S100A10; S100A6; CC10; ANXA4; ANXA5; ANXA2; ANXA6; ANXA3

Protein Function

S100A6 has several biochemical functions, for example, S100 protein binding, calcium ion binding, calcium-dependent protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S100A6 itself. We selected most functions S100A6 had, and list some proteins which have the same functions with S100A6. You can find most of the proteins on our site.
Function
Related Protein
Function S100 protein binding
Related Protein EZR; S100B; ANXA2; S100A6; S100A11; FGF1A; DDX1; KCNK3; ANXA11; S100A1
Function calcium ion binding
Related Protein CAPN11; FBLN2; BNIP2; MASP2; MMP28; CALM3A; OCM2; PLCH2; RASGRP1; EFCAB7
Function calcium-dependent protein binding
Related Protein DDX5; MBL2; ANXA3; NRXN1; RAC3; CLEC4M; VPS37B; ANXA6; TNNC1; VLDLR
Function ion transmembrane transporter activity
Related Protein SFXN2; TRPV2; SFXN1; SFXN5A; PLP2; LASP1; S100A6; SFXN3; GJA1; SFXN4
Function protein binding
Related Protein DNAJA4; PASK; EXOC1; MALL; COA5; LEPR; Arid4b; NPHP1; STAT5A; ALDOC
Function protein homodimerization activity
Related Protein FBXO4; TCF4; GDF6; CADM2A; CRYBA1; HLA-G; HHEX; DRD2; NR4A3; GSTM1
Function tropomyosin binding
Related Protein TNNT1; LMOD1; S100A6; CALD1; NEBL; PYCARD; TMOD2; TNNT3; LMOD2A; TMOD3
Function zinc ion binding
Related Protein ZDHHC14; CA5; PXNA; ADAMTSL3; LMO7A; FBXO30B; UQCRC2A; TCEA1; ZNF346; ISL2

Interacting Protein

S100A6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S100A6 here. Most of them are supplied by our site. Hope this information will be useful for your research of S100A6.
KPNA2; PPID; FKBP4; PEX5; MDM2; S100B; TP53

S100A6 Related Articles

Meghnani, V; Wagh, A; et al. The receptor for advanced glycation end products influences the expression of its S100 protein ligands in melanoma tumors. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 57:54-62(2014).
Jurewicz, E; Goral, A; et al. S100A6 is secreted from Wharton's jelly mesenchymal stem cells and interacts with integrin beta 1. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 55:298-303(2014).