TNFRSF13B

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TNFRSF13B

Official Full Name tumor necrosis factor receptor superfamily, member 13B
Background The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17.
Synonyms TNFRSF13B; tumor necrosis factor receptor superfamily, member 13B; CVID; TACI; CD267; FLJ39942; MGC39952; MGC133214; TNFRSF14B; Tumor necrosis factor receptor superfamily member 13B; Transmembrane activator and CAML interactor; OTTHUMP00000065442; CD267 antigen; tumor necrosis factor receptor 13B
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus monkey
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • NSO
    • Tag :
    • Avi
    • Fc
    • GST
    • hIgG1
    • hIgG4
    • His
    • human
    • IgG1
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TNFRSF13B-359H Recombinant Human TNFRSF13B protein, Fc-tagged HEK293 human/IgG1/Fc
    Mouse Tnfrsf13b-6545M Recombinant Mouse Tnfrsf13b Protein, Fc-tagged HEK293 Fc
    Human TNFRSF13B-694H Recombinant Human TNFRSF13B Protein, Fc-Avi-tagged, Biotinylated HEK293 Avi/Fc
    Human TNFRSF13B-1683H Recombinant Human TNFRSF13B, Fc-tagged NSO Fc
    Human TNFRSF13B-1916HCL Recombinant Human TNFRSF13B cell lysate Human Cell N/A
    Human TNFRSF13B-2095H Recombinant Human TNFRSF13B, Fc-tagged HEK293 Fc
    Human TNFRSF13B-3320H Recombinant Human TNFRSF13B, GST-tagged E.coli GST
    Human TNFRSF13B-506H Recombinant Human TNFRSF13B Protein, Fc-tagged HEK293 Fc
    Human TNFRSF13B-567H Recombinant Human TNFRSF13B, His tagged Human Cell His
    Human TNFRSF13B-693H Recombinant Human TNFRSF13B, Fc-tagged, Biotinylated Human Cell Fc
    Human TNFRSF13B-7545H Recombinant Human TNFRSF13B, His-tagged E.coli His
    Human TNFRSF13B-970H Recombinant Human TNFRSF13B protein E.coli N/A
    Human TNFRSF13B-P05H Recombinant Human TACI, Fc-tagged (Atacicept) Fc
    Rhesus monkey TNFRSF13B-1648R Recombinant Rhesus Monkey TNFRSF13B Protein HEK293 N/A
    Rhesus monkey TNFRSF13B-1649R Recombinant Rhesus Monkey TNFRSF13B Protein, hIgG1-tagged HEK293 hIgG1
    Rhesus monkey TNFRSF13B-1650R Recombinant Rhesus Monkey TNFRSF13B Protein, hIgG4-tagged HEK293 hIgG4
    Chicken TNFRSF13B-3698C Recombinant Chicken TNFRSF13B Mammalian Cell His

    TNFRSF13B involved in several pathways and played different roles in them. We selected most pathways TNFRSF13B participated on our site, such as Cytokine-cytokine receptor interaction, Intestinal i, ne network for IgA production, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNFRSF13B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction CCR7; IL2RB; IFNL3; IFN-a; Ifnlr1; INHBA; IFNA16; CCL21; CCL27B; IFNG
    Intestinal i CD40LG; CXCL12B; Icosl; MHC2DEB; CCL27B; MADCAM1; ICOS; H2-AB1; CXCR4; ICOSLG
    ne network for IgA production CXCL12; HLA-DRB4; BLB2; CCR10; H2-AB1; HLA-DPA1; CD28; Icosl; CXCL12A; IL5
    Primary i CD8A; RAG2; IL2RG; CD3E; RFXANK; CD4; TAP2; IGLL1; IL7R; CD8B
    nodeficiency AICDA; IKBKG; CD40; CD8B; ICOS; TAP2; CD40LG; CD3D; CD19; RAG2

    TNFRSF13B has several biochemical functions, for example, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TNFRSF13B itself. We selected most functions TNFRSF13B had, and list some proteins which have the same functions with TNFRSF13B. You can find most of the proteins on our site.

    Function Related Protein
    protein binding BCAP31; GMNN; PBX4; MAT2B; PSENEN; RBM15; PDXP; DUSP13; HMOX2; EIF2S2
    receptor activity CADM3; RTN4R; PVRL3; NLGN2A; TLR6; CD4; NLGN3A; NLGN2B; SV2A; DARC

    TNFRSF13B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNFRSF13B here. Most of them are supplied by our site. Hope this information will be useful for your research of TNFRSF13B.

    TNFSF13B; MYD88; SGTA

    Chew, G; Gatenby, P; et al. TNFRSF13B VARIANTS IN SYSTEMIC LUPUS ERYTHEMATOSUS AND PRIMARY ANTIBODY DEFICIENCY. INTERNAL MEDICINE JOURNAL 44:6-7(2014).
    Martinez-Gallo, M; Radigan, L; et al. TACI mutations and impaired B-cell function in subjects with CVID and healthy heterozygotes. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 131:468-476(2013).

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